Interactor 1: APBB1 (O00213)
Amyloid beta precursor protein binding family B member 1 (Amyloid-beta A4 precursor protein-binding family B member 1) (Protein Fe65)
Gene: APBB1

Interactor 2: APBB2 (Q92870)
Amyloid beta precursor protein binding family B member 2 (Amyloid-beta (A4) precursor protein-binding family B member 2) (Protein Fe65-like 1)
Gene: APBB2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.74 1.00 0.861

The method score is based on:

Property Details
Experiments 26186194, 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains PID~PID, WW~WW
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0001540 - amyloid-beta binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005783 - endoplasmic reticulum
and 7 others

more...

Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 710
Hs

1 758
+ Hs
+ Mm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024