HitPredict

Interactor 1: BEE1 (Q8GZ13)
Transcription factor BEE 1 (Basic helix-loop-helix protein 44) (AtbHLH44) (bHLH 44) (Protein Brassinosteroid enhanced expression 1) (Transcription factor EN 77) (bHLH transcription factor bHLH044)
Gene: BEE1

Interactor 2: HEC3 (Q9LXD8)
Transcription factor HEC3 (Basic helix-loop-helix protein 43) (AtbHLH43) (bHLH 43) (Protein HECATE 3) (Transcription factor EN 119) (bHLH transcription factor bHLH043)
Gene: HEC3

Species: Arabidopsis thaliana

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.63	1.00	0.800

Property	Details
Experiments	28650476, 36088536
Identification Methods	two hybrid, Cr-two hybrid, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	HLH~HLH
Common GO terms	GO:0003677 - DNA binding GO:0003700 - DNA-binding transcription factor activity GO:0005634 - nucleus GO:0006355 - regulation of DNA-templated transcription GO:0046983 - protein dimerization activity
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 260 At			1 224
+	At
		1210119 BEE1_ARATH (1-260): 9.3e-58: 186: 100.00		HEC1_ARATH (5-185): 1.43e-35: 127: 48.91
+	At
		59896 BEE1_ARATH (1-260): 9.3e-58: 186: 100.00		BH075_ARATH (19-218): 4.45e-33: 120: 22.28
+	At
		1196557 BEE1_ARATH (1-260): 9.3e-58: 186: 100.00		RSL2_ARATH (67-204): 1.21e-30: 117: 33.33
+	At
		1210126 BEE1_ARATH (1-260): 9.3e-58: 186: 100.00		HEC2_ARATH (41-185): 8.47e-32: 117: 52.29
+	At
		286569 BEE1_ARATH (1-260): 9.3e-58: 186: 100.00		IND_ARATH (94-190): 6.75e-31: 114: 75.26
+	At
		1210118 BEE1_ARATH (1-260): 9.3e-58: 186: 100.00		RHD6_ARATH (113-202): 1.44e-25: 102: 42.55
+	At
		1210122 BEE1_ARATH (1-260): 9.3e-58: 186: 100.00		SPT_ARATH (126-191): 3.13e-22: 94.9: 39.39
+	At
		1275069 BH137_ARATH (1-256): 8.78e-38: 135: 29.92		HEC3_ARATH (1-224): 2.85e-39: 136: 100.00
+	At
		59895 BEE3_ARATH (6-260): 1.49e-38: 137: 53.79		BH075_ARATH (19-218): 4.45e-33: 120: 22.28
+	At
		1274971 BH137_ARATH (1-256): 8.78e-38: 135: 29.92		BEE2_ARATH (7-219): 6.46e-32: 119: 18.75
+	At
		1209823 BH063_ARATH (68-241): 6.29e-37: 134: 36.21		BEE2_ARATH (7-219): 6.46e-32: 119: 18.75
+	At
		1274982 BH077_ARATH (1-234): 3.08e-36: 133: 31.20		BEE2_ARATH (7-219): 6.46e-32: 119: 18.75
+	At
		1209825 BH076_ARATH (28-255): 3.07e-36: 134: 30.70		BH063_ARATH (80-214): 1.1e-30: 117: 27.94
+	At
		285433 PIF3_ARATH (21-218): 1.33e-35: 134: 20.00		PIF3_ARATH (20-191): 8.09e-29: 114: 25.00
+	At
		1209850 BH063_ARATH (68-241): 6.29e-37: 134: 36.21		BH062_ARATH (9-210): 1.21e-28: 113: 24.14
+	At
		1275068 BH137_ARATH (1-256): 8.78e-38: 135: 29.92		BH079_ARATH (78-190): 1.59e-26: 105: 27.19
+	At
		1209838 BH063_ARATH (68-241): 6.29e-37: 134: 36.21		BH079_ARATH (78-190): 1.59e-26: 105: 27.19
+	At
		1338417 BH077_ARATH (1-234): 3.08e-36: 133: 31.20		BH079_ARATH (78-190): 1.59e-26: 105: 27.19
+	At
		285447 PIF3_ARATH (21-218): 1.33e-35: 134: 20.00		PIF1_ARATH (106-213): 3.65e-23: 98.3: 34.82