HitPredict

Interactor 1: LEG8 (O00214)
Galectin-8 (Gal-8) (Po66 carbohydrate-binding protein) (Po66-CBP) (Prostate carcinoma tumor antigen 1) (PCTA-1)
Gene: LGALS8

Interactor 2: ITAV (P06756)
Integrin alpha-V (Vitronectin receptor) (Vitronectin receptor subunit alpha) (CD antigen CD51) [Cleaved into: Integrin alpha-V heavy chain; Integrin alpha-V light chain]
Gene: ITGAV

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	18849583
Identification Methods	pull down
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005178 - integrin binding GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 317 Hs			1 1048
+	Hs
		121084 LEG8_HUMAN (1-317): 8.73e-135: 386: 100.00		ITA5_HUMAN (28-1044): 0: 1041: 45.44
+	Hs
		119100 LEG9_HUMAN (3-316): 1.06e-111: 329: 30.83		ITA5_HUMAN (28-1044): 0: 1041: 45.44
+	Hs
		419138 LEG1_HUMAN (192-314): 3.25e-38: 133: 31.50		ITAV_HUMAN (28-1048): 0: 1193: 100.00
+	Hs
		121107 LEG8_HUMAN (1-317): 8.73e-135: 386: 100.00		ITA6_HUMAN (9-1040): 0: 904: 25.48
+	Hs
		121095 LEG8_HUMAN (1-317): 8.73e-135: 386: 100.00		ITA4_HUMAN (1-1047): 0: 882: 25.37
+	Hs
		121150 LEG8_HUMAN (1-317): 8.73e-135: 386: 100.00		ITA7_HUMAN (5-1043): 0: 881: 26.13
+	Mm
		139224 LEG9_MOUSE (3-316): 6.48e-117: 342: 34.08		ITA2B_MOUSE (16-1028): 0: 924: 37.17
+	Hs
		119131 LEG9_HUMAN (3-316): 1.06e-111: 329: 30.83		ITA4_HUMAN (1-1047): 0: 882: 25.37
+	Hs
		443032 LEG3_HUMAN (16-153): 2.84e-45: 155: 39.72		ITA5_HUMAN (28-1044): 0: 1041: 45.44
+	Hs
		121110 LEG8_HUMAN (1-317): 8.73e-135: 386: 100.00		ITA3_HUMAN (12-1047): 0: 800: 25.63
+	Hs
		443022 LEG1_HUMAN (192-314): 3.25e-38: 133: 31.50		ITA5_HUMAN (28-1044): 0: 1041: 45.44
+	Hs
		449172 LEG1_HUMAN (192-314): 3.25e-38: 133: 31.50		ITA4_HUMAN (1-1047): 0: 882: 25.37
+	Hs
		121135 LEG8_HUMAN (1-317): 8.73e-135: 386: 100.00		ITA1_HUMAN (5-166): 1.5e-39: 161: 26.38
+	Hs
		121102 LEG8_HUMAN (1-317): 8.73e-135: 386: 100.00		ITA2_HUMAN (24-175): 3.08e-30: 131: 22.58
+	Hs
		121106 LEG8_HUMAN (1-317): 8.73e-135: 386: 100.00		ITAL_HUMAN (13-176): 3.8e-24: 111: 19.76
+	Hs
		119160 LEG9_HUMAN (3-316): 1.06e-111: 329: 30.83		ITAL_HUMAN (13-176): 3.8e-24: 111: 19.76
+	Hs
		572330 LEG3_HUMAN (16-153): 2.84e-45: 155: 39.72		ITA1_HUMAN (5-166): 1.5e-39: 161: 26.38
+	Hs
		566849 LEG3_HUMAN (16-153): 2.84e-45: 155: 39.72		ITA2_HUMAN (24-175): 3.08e-30: 131: 22.58
+	Hs
		506097 LEG3_HUMAN (16-153): 2.84e-45: 155: 39.72		ITAM_HUMAN (20-168): 1.61e-25: 116: 23.18
+	Hs
		449180 LEG1_HUMAN (192-314): 3.25e-38: 133: 31.50		ITA2_HUMAN (24-175): 3.08e-30: 131: 22.58