HitPredict

Interactor 1: APC2 (Q8H1U5)
Anaphase-promoting complex subunit 2 (Cyclosome subunit 2)
Gene: APC2

Interactor 2: CDC23 (Q9STS3)
Anaphase-promoting complex subunit 8 (Cell division cycle protein 23 homolog) (CDC23 homolog) (Cyclosome subunit 8)
Gene: APC8

Species: Arabidopsis thaliana

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.620

Property	Details
Experiments	14508008, 20706207
Identification Methods	two hybrid, affinity chromatography technology, tandem affinity purification
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005680 - anaphase-promoting complex GO:0051301 - cell division
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 865 At			1 579
+	At
		1210826 APC2_ARATH (1-865): 0: 902: 100.00		APC7_ARATH (67-572): 2.35e-54: 195: 17.55
+	At
		71742 APC2_ARATH (1-865): 0: 902: 100.00		CDC16_ARATH (95-466): 6.03e-22: 101: 12.65
+	At
		1210824 APC2_ARATH (1-865): 0: 902: 100.00		CD27B_ARATH (346-579): 2.44e-18: 91.1: 14.53
+	At
		989581 APC2_ARATH (1-865): 0: 902: 100.00		CD27A_ARATH (346-579): 2.64e-17: 87.6: 12.82
+	Hs
		1135067 ANC2_HUMAN (49-865): 0: 674: 30.43		Q5T8C6_HUMAN (146-496): 9.62e-78: 255: 19.44
+	Hs
		672920 ANC2_HUMAN (49-865): 0: 674: 30.43		CDC27_HUMAN (71-338): 8.44e-26: 114: 11.55
+	Hs
		1356135 ANC2_HUMAN (49-865): 0: 674: 30.43		APC7_HUMAN (175-579): 3.87e-21: 99.2: 10.25
+	Dm
		1337224 Q9W1E5_DROME (76-865): 0: 641: 29.43		Q9I7L8_DROME (135-579): 1.27e-20: 98: 11.44
+	Hs
		1356112 ANC2_HUMAN (49-865): 0: 674: 30.43		CDC23_HUMAN (275-579): 9.2e-10: 63.3: 12.91
+	Hs
		1023019 ANC2_HUMAN (49-865): 0: 674: 30.43		CDC16_HUMAN (70-345): 2.04e-09: 62.2: 9.56
+	Sc
		561135 APC2_YEAST (356-865): 4.89e-117: 377: 21.94		CDC23_YEAST (7-566): 1.5e-53: 194: 27.98
+	Hs
		1042800 CUL3_HUMAN (115-854): 2.34e-131: 413: 14.39		APC7_HUMAN (175-579): 3.87e-21: 99.2: 10.25
+	Hs
		174870 CUL4B_HUMAN (383-853): 2.64e-131: 417: 15.51		OGT1_HUMAN (2-223): 4.44e-17: 87.2: 9.91
+	Hs
		174869 CUL3_HUMAN (115-854): 2.34e-131: 413: 14.39		OGT1_HUMAN (2-223): 4.44e-17: 87.2: 9.91
+	Hs
		1022896 CUL3_HUMAN (115-854): 2.34e-131: 413: 14.39		CDC16_HUMAN (70-345): 2.04e-09: 62.2: 9.56
+	Hs
		1043287 CUL4A_HUMAN (175-853): 7.03e-131: 411: 15.16		CDC23_HUMAN (275-579): 9.2e-10: 63.3: 12.91
+	Sc
		743238 APC2_YEAST (356-865): 4.89e-117: 377: 21.94		CDC27_YEAST (92-405): 8.01e-19: 92.6: 11.98
+	Sp
		489653 APC2_SCHPO (158-864): 1.49e-112: 360: 28.37		APC3_SCHPO (342-578): 1.52e-21: 100: 12.66
+	Sc
		454934 APC2_YEAST (356-865): 4.89e-117: 377: 21.94		CDC16_YEAST (212-578): 1.99e-13: 75.3: 10.27
+	Sp
		784812 APC2_SCHPO (158-864): 1.49e-112: 360: 28.37		CUT9_SCHPO (197-578): 8.34e-10: 63.7: 11.57