HitPredict

Interactor 1: LEG8 (O00214)
Galectin-8 (Gal-8) (Po66 carbohydrate-binding protein) (Po66-CBP) (Prostate carcinoma tumor antigen 1) (PCTA-1)
Gene: LGALS8

Interactor 2: CO4A (P0C0L4)
Complement C4-A (Acidic complement C4) (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2) [Cleaved into: Complement C4 beta chain; Complement C4-A alpha chain; C4a anaphylatoxin; C4b-A; C4d-A; Complement C4 gamma chain]
Gene: C4A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005615 - extracellular space
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 317 Hs			1 1744
+	Hs
		121068 LEG8_HUMAN (1-317): 8.73e-135: 386: 100.00		A2MG_HUMAN (15-1578): 0: 1440: 22.22
+	Hs
		119065 LEG9_HUMAN (3-316): 1.06e-111: 329: 30.83		A2MG_HUMAN (15-1578): 0: 1440: 22.22
+	Hs
		344637 LEG3_HUMAN (16-153): 2.84e-45: 155: 39.72		CO3_HUMAN (20-1742): 0: 1532: 27.81
+	Hs
		344434 LEG3_HUMAN (16-153): 2.84e-45: 155: 39.72		A2MG_HUMAN (15-1578): 0: 1440: 22.22
+	Hs
		119426 LEG9_HUMAN (3-316): 1.06e-111: 329: 30.83		CD109_HUMAN (4-1596): 0: 1207: 22.17
+	Hs
		572387 LEG3_HUMAN (16-153): 2.84e-45: 155: 39.72		CD109_HUMAN (4-1596): 0: 1207: 22.17
+	Hs
		449301 LEG1_HUMAN (192-314): 3.25e-38: 133: 31.50		CD109_HUMAN (4-1596): 0: 1207: 22.17