HitPredict

Interactor 1: LEG8 (O00214)
Galectin-8 (Gal-8) (Po66 carbohydrate-binding protein) (Po66-CBP) (Prostate carcinoma tumor antigen 1) (PCTA-1)
Gene: LGALS8

Interactor 2: VGFR3 (P35916)
Vascular endothelial growth factor receptor 3 (VEGFR-3) (EC 2.7.10.1) (Fms-like tyrosine kinase 4) (FLT-4) (Tyrosine-protein kinase receptor FLT4)
Gene: FLT4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 317 Hs			1 1363
+	Hs
		572301 LEG3_HUMAN (16-153): 2.84e-45: 155: 39.72		VGFR3_HUMAN (1-1363): 0: 982: 100.00
+	Hs
		449210 LEG1_HUMAN (192-314): 3.25e-38: 133: 31.50		VGFR3_HUMAN (1-1363): 0: 982: 100.00
+	Hs
		449211 LEG1_HUMAN (192-314): 3.25e-38: 133: 31.50		VGFR2_HUMAN (1-1346): 0: 879: 42.21
+	Hs
		449182 LEG1_HUMAN (192-314): 3.25e-38: 133: 31.50		VGFR1_HUMAN (19-1342): 0: 828: 38.63
+	Hs
		121093 LEG8_HUMAN (1-317): 8.73e-135: 386: 100.00		FGFR1_HUMAN (2-160): 6.17e-14: 78.9: 11.93
+	Hs
		449252 LEG1_HUMAN (192-314): 3.25e-38: 133: 31.50		PTK7_HUMAN (2-331): 1.72e-50: 197: 14.16