HitPredict

Interactor 1: LEG8 (O00214)
Galectin-8 (Gal-8) (Po66 carbohydrate-binding protein) (Po66-CBP) (Prostate carcinoma tumor antigen 1) (PCTA-1)
Gene: LGALS8

Interactor 2: LRC8E (Q6NSJ5)
Volume-regulated anion channel subunit LRRC8E (Leucine-rich repeat-containing protein 8E)
Gene: LRRC8E

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 317 Hs			1 796
+	Hs
		119370 LEG9_HUMAN (3-316): 1.06e-111: 329: 30.83		SCRIB_HUMAN (485-794): 7.75e-69: 250: 28.21
+	Hs
		121187 LEG8_HUMAN (1-317): 8.73e-135: 386: 100.00		LRC8A_HUMAN (467-796): 1.41e-33: 140: 21.39
+	Hs
		121195 LEG8_HUMAN (1-317): 8.73e-135: 386: 100.00		LRC8C_HUMAN (485-796): 3.55e-33: 139: 21.00
+	Hs
		119441 LEG9_HUMAN (3-316): 1.06e-111: 329: 30.83		LRC8A_HUMAN (467-796): 1.41e-33: 140: 21.39
+	Hs
		1107975 LEG9B_HUMAN (3-316): 3.69e-110: 325: 30.47		LRC8A_HUMAN (467-796): 1.41e-33: 140: 21.39