HitPredict

Interactor 1: LEG8 (O00214)
Galectin-8 (Gal-8) (Po66 carbohydrate-binding protein) (Po66-CBP) (Prostate carcinoma tumor antigen 1) (PCTA-1)
Gene: LGALS8

Interactor 2: NECT3 (Q9NQS3)
Nectin-3 (CDw113) (Nectin cell adhesion molecule 3) (Poliovirus receptor-related protein 3) (CD antigen CD113)
Gene: NECTIN3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.80	0.705

Property	Details
Experiments	26186194, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Gal-bind_lectin~V-set
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 317 Hs			1 549
+	Hs
		121183 LEG8_HUMAN (1-317): 8.73e-135: 386: 100.00		SDK1_HUMAN (5-499): 7.02e-34: 139: 13.50
+	Hs
		121158 LEG8_HUMAN (1-317): 8.73e-135: 386: 100.00		NECT1_HUMAN (3-275): 1.18e-13: 75.5: 10.91
+	Hs
		449360 LEG1_HUMAN (192-314): 3.25e-38: 133: 31.50		NECT3_HUMAN (49-549): 5.39e-105: 327: 100.00
+	Hs
		119138 LEG9_HUMAN (3-316): 1.06e-111: 329: 30.83		PVR_HUMAN (2-269): 4.78e-10: 63.8: 13.33
+	Hs
		572370 LEG3_HUMAN (16-153): 2.84e-45: 155: 39.72		SDK2_HUMAN (39-476): 2.32e-34: 140: 12.92
+	Hs
		572394 LEG3_HUMAN (16-153): 2.84e-45: 155: 39.72		SDK1_HUMAN (5-499): 7.02e-34: 139: 13.50
+	Hs
		814965 LEG7_HUMAN (184-315): 1.04e-42: 145: 36.57		SDK2_HUMAN (39-476): 2.32e-34: 140: 12.92
+	Hs
		814978 LEG7_HUMAN (184-315): 1.04e-42: 145: 36.57		SDK1_HUMAN (5-499): 7.02e-34: 139: 13.50
+	Hs
		449281 LEG1_HUMAN (192-314): 3.25e-38: 133: 31.50		SDK2_HUMAN (39-476): 2.32e-34: 140: 12.92
+	Hs
		449306 LEG1_HUMAN (192-314): 3.25e-38: 133: 31.50		SDK1_HUMAN (5-499): 7.02e-34: 139: 13.50
+	Hs
		572445 LEG3_HUMAN (16-153): 2.84e-45: 155: 39.72		CADM1_HUMAN (4-255): 1.27e-18: 90.4: 14.90
+	Hs
		545068 LEG3_HUMAN (16-153): 2.84e-45: 155: 39.72		PVR_HUMAN (2-269): 4.78e-10: 63.8: 13.33