HitPredict

Interactor 1: Q8IMZ2 (Q8IMZ2)
Oo18 RNA-binding protein, isoform C (Oo18 RNA-binding protein, isoform E)
Gene: orb

Interactor 2: Q8SYC0 (Q8SYC0)
Bruno 1, isoform D (RE72594p)
Gene: bru1

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.624

Property	Details
Experiments	21949709, 12538512
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003729 - mRNA binding GO:0003730 - mRNA 3'-UTR binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0007281 - germ cell development and 1 others more... GO:1990904 - ribonucleoprotein complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 559 Dm			1 361
+	Dm
		597059 Q8IMZ2_DROME (1-559): 1.08e-149: 443: 100.00		PABP_DROME (2-264): 5.38e-15: 78.2: 13.69
+	Hs
		1077485 CPEB1_HUMAN (172-466): 3.54e-88: 284: 57.10		ELAV1_HUMAN (259-361): 2.17e-27: 111: 32.11
+	Hs
		1020324 CPEB1_HUMAN (172-466): 3.54e-88: 284: 57.10		ELAV2_HUMAN (260-355): 5.15e-26: 108: 31.25
+	Hs
		1031450 CPEB1_HUMAN (172-466): 3.54e-88: 284: 57.10		PABP4_HUMAN (5-253): 1.63e-22: 100: 7.58
+	Hs
		1077381 CPEB4_HUMAN (175-476): 3.97e-80: 267: 36.66		ELAV1_HUMAN (259-361): 2.17e-27: 111: 32.11
+	Hs
		1031349 CPEB4_HUMAN (175-476): 3.97e-80: 267: 36.66		PABP4_HUMAN (5-253): 1.63e-22: 100: 7.58
+	Hs
		516680 CPEB1_HUMAN (172-466): 3.54e-88: 284: 57.10		PABP1_HUMAN (2-266): 1.06e-15: 80.1: 14.29
+	Dm
		1373699 ORB2_DROME (187-475): 3.64e-77: 259: 34.62		Q9VYI0_DROME (277-358): 6.01e-20: 91.6: 26.00
+	Hs
		1089544 CPEB4_HUMAN (175-476): 3.97e-80: 267: 36.66		CELF1_HUMAN (3-150): 2.5e-16: 82: 27.45
+	Hs
		516539 CPEB4_HUMAN (175-476): 3.97e-80: 267: 36.66		PABP1_HUMAN (2-266): 1.06e-15: 80.1: 14.29
+	Dm
		333218 O97468_DROME (111-544): 4.47e-55: 196: 14.25		Q9VYI0_DROME (277-358): 6.01e-20: 91.6: 26.00
+	Dm
		1213881 Q8SXP8_DROME (111-544): 7.76e-55: 195: 14.03		Q8IP90_DROME (265-359): 3.57e-16: 82.1: 21.21
+	Hs
		516689 PABP3_HUMAN (211-528): 2.49e-40: 157: 11.21		PABP1_HUMAN (2-266): 1.06e-15: 80.1: 14.29
+	Hs
		474021 PABP4_HUMAN (91-351): 1.35e-21: 100: 9.30		PAB4L_HUMAN (79-360): 1.72e-29: 118: 12.06
+	Mm
		449421 NUCL_MOUSE (1-298): 3.91e-23: 105: 12.33		ELAV1_MOUSE (277-361): 1.15e-26: 110: 35.56
+	Hs
		1020249 PABP4_HUMAN (91-351): 1.35e-21: 100: 9.30		ELAV2_HUMAN (260-355): 5.15e-26: 108: 31.25
+	Hs
		201697 MSI1H_HUMAN (146-324): 5.49e-30: 123: 11.62		CELF1_HUMAN (3-150): 2.5e-16: 82: 27.45
+	Hs
		201689 MSI1H_HUMAN (146-324): 5.49e-30: 123: 11.62		CELF5_HUMAN (2-151): 5.01e-15: 77.8: 20.53
+	Hs
		516355 NUCL_HUMAN (178-514): 9.12e-22: 101: 10.69		PABP1_HUMAN (2-266): 1.06e-15: 80.1: 14.29
+	Hs
		516495 PABP4_HUMAN (91-351): 1.35e-21: 100: 9.30		PABP1_HUMAN (2-266): 1.06e-15: 80.1: 14.29