HitPredict

Interactor 1: FRU (Q8IN81)
Sex determination protein fruitless
Gene: FRU

Interactor 2: HDAC1 (Q94517)
Histone deacetylase HDAC1 (HD) (EC 3.5.1.98)
Gene: HDAC1

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	22682252
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 955 Dm			1 521
+	Hs
		781407 BCL6_HUMAN (107-539): 5.44e-54: 202: 14.13		HDAC2_HUMAN (2-488): 0: 659: 76.59
+	Hs
		984006 ZBT16_HUMAN (108-368): 2.26e-50: 191: 20.58		HDAC2_HUMAN (2-488): 0: 659: 76.59
+	Hs
		781362 BCL6_HUMAN (107-539): 5.44e-54: 202: 14.13		HDAC1_HUMAN (3-443): 0: 637: 81.18
+	Hs
		1235582 ZBTB2_HUMAN (112-518): 5.65e-46: 175: 15.35		HDAC2_HUMAN (2-488): 0: 659: 76.59
+	Hs
		317598 ZBT11_HUMAN (72-461): 5.43e-51: 197: 14.32		HDAC1_HUMAN (3-443): 0: 637: 81.18
+	Mm
		140266 Q3UQ17_MOUSE (108-402): 2.9e-50: 191: 18.46		HDAC1_MOUSE (3-443): 0: 640: 81.18
+	Hs
		983971 ZBT16_HUMAN (108-368): 2.26e-50: 191: 20.58		HDAC1_HUMAN (3-443): 0: 637: 81.18
+	Mm
		140251 BACH1_MOUSE (101-485): 1.39e-48: 187: 14.90		HDAC1_MOUSE (3-443): 0: 640: 81.18
+	Hs
		1038538 ZBTB2_HUMAN (112-518): 5.65e-46: 175: 15.35		HDAC1_HUMAN (3-443): 0: 637: 81.18
+	Hs
		200286 ZBT43_HUMAN (101-488): 1.82e-46: 175: 14.29		HDAC1_HUMAN (3-443): 0: 637: 81.18
+	Hs
		1038494 KAISO_HUMAN (101-529): 1.57e-44: 174: 14.96		HDAC1_HUMAN (3-443): 0: 637: 81.18
+	Hs
		1038838 ZBTB1_HUMAN (111-470): 3.21e-42: 167: 16.58		HDAC1_HUMAN (3-443): 0: 637: 81.18
+	Mm
		140211 ZBT7A_MOUSE (100-425): 6.49e-41: 161: 15.77		HDAC1_MOUSE (3-443): 0: 640: 81.18
+	Hs
		177221 BCL6_HUMAN (107-539): 5.44e-54: 202: 14.13		HDAC3_HUMAN (6-427): 0: 572: 56.37
+	Hs
		177270 ZBT16_HUMAN (108-368): 2.26e-50: 191: 20.58		HDAC3_HUMAN (6-427): 0: 572: 56.37
+	Hs
		177376 BACH2_HUMAN (96-544): 5.33e-47: 183: 15.37		HDAC3_HUMAN (6-427): 0: 572: 56.37
+	Hs
		177334 KAISO_HUMAN (101-529): 1.57e-44: 174: 14.96		HDAC3_HUMAN (6-427): 0: 572: 56.37
+	Hs
		781333 BCL6_HUMAN (107-539): 5.44e-54: 202: 14.13		HDAC4_HUMAN (5-405): 2.08e-133: 415: 22.86
+	Hs
		880692 ZBT16_HUMAN (108-368): 2.26e-50: 191: 20.58		HDAC4_HUMAN (5-405): 2.08e-133: 415: 22.86
+	Hs
		984038 ZBT16_HUMAN (108-368): 2.26e-50: 191: 20.58		HDAC6_HUMAN (9-323): 1.24e-99: 327: 23.55