Interactor 1: Q8IP45 (Q8IP45)
Cullin 3, isoform F (FI19425p1)
Gene: Cul3

Interactor 2: UBC2M (Q9VSF3)
Nedd8-conjugating enzyme UbcE2M (EC 2.3.2.34) (Nedd8 carrier protein)
Gene: UbcE2M

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 21931660
Identification Methods enzymatic study
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Cullin_Nedd8~UQ_con
Common GO terms GO:0045879 - negative regulation of smoothened signaling pathway
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 934
Dm

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024