Interactor 1: TR10A (O00220)
Tumor necrosis factor receptor superfamily member 10A (Death receptor 4) (TNF-related apoptosis-inducing ligand receptor 1) (TRAIL receptor 1) (TRAIL-R1) (CD antigen CD261)
Gene: TNFRSF10A
Interactor 2: TR10B (O14763)
Tumor necrosis factor receptor superfamily member 10B (Death receptor 5) (TNF-related apoptosis-inducing ligand receptor 2) (TRAIL receptor 2) (TRAIL-R2) (CD antigen CD262)
Gene: TNFRSF10B
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.85 | 1.00 | 0.927 |
The method score is based on:
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | Death~Death, TNFR_c6~TNFR_c6 |
Common GO terms | GO:0005886 - plasma membrane GO:0006915 - apoptotic process GO:0007250 - activation of NF-kappaB-inducing kinase activity GO:0008625 - extrinsic apoptotic signaling pathway via death domain receptors GO:0009986 - cell surface and 5 others more... |
Homologous interactions | 16 |
Homologous interactions
Color coding for hit scores
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024