HitPredict

Interactor 1: IKBE (O00221)
NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkB-E) (IkB-epsilon) (IkappaBepsilon)
Gene: NFKBIE

Interactor 2: XPO1 (O14980)
Exportin-1 (Exp1) (Chromosome region maintenance 1 protein homolog)
Gene: XPO1

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	26673895, 11970947
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 500 Hs			1 1071
+	Xl
		1117304 Q4KLR5_XENLA (149-499): 1.44e-68: 225: 49.86		Q6NS03_XENLA (1-1071): 0: 1007: 97.01
+	Hs
		163457 ANR50_HUMAN (192-500): 5.54e-56: 203: 18.24		XPO1_HUMAN (1-1071): 0: 1022: 100.00
+	Hs
		162776 IKBB_HUMAN (254-447): 4.47e-26: 110: 37.50		XPO1_HUMAN (1-1071): 0: 1022: 100.00
+	Hs
		162298 TNKS1_HUMAN (6-279): 3.79e-24: 108: 10.58		XPO1_HUMAN (1-1071): 0: 1022: 100.00
+	Hs
		163272 Q9H4D1_HUMAN (403-500): 4.98e-15: 79.8: 23.47		XPO1_HUMAN (1-1071): 0: 1022: 100.00
+	Hs
		163008 ANR52_HUMAN (298-488): 3.21e-13: 74.3: 33.85		XPO1_HUMAN (1-1071): 0: 1022: 100.00
+	Hs
		162399 NFKB1_HUMAN (386-481): 8.64e-13: 72.8: 24.51		XPO1_HUMAN (1-1071): 0: 1022: 100.00
+	Hs
		162419 IKBA_HUMAN (252-330): 1.11e-12: 70.9: 30.00		XPO1_HUMAN (1-1071): 0: 1022: 100.00
+	Hs
		162635 NFKB2_HUMAN (420-500): 5.33e-09: 60.9: 23.00		XPO1_HUMAN (1-1071): 0: 1022: 100.00
+	Xl
		1150110 Q6DCW3_XENLA (246-348): 3.39e-12: 69.4: 25.00		Q6NS03_XENLA (1-1071): 0: 1007: 97.01
+	Xl
		251120 NFKB2_XENLA (245-362): 1.21e-10: 66.3: 20.00		Q6NS03_XENLA (1-1071): 0: 1007: 97.01
+	Mm
		1119759 ANR28_MOUSE (30-458): 1.19e-51: 191: 15.51		XPO7_MOUSE (23-1013): 5.43e-120: 397: 13.01
+	Hs
		1206059 MIB1_HUMAN (166-500): 1.3e-69: 241: 23.85		XPO5_HUMAN (26-665): 5.8e-100: 344: 16.12
+	Mm
		71300 ANR44_MOUSE (16-364): 7.56e-35: 141: 11.94		XPO7_MOUSE (23-1013): 5.43e-120: 397: 13.01
+	Hs
		155558 RIPK4_HUMAN (381-500): 5.47e-16: 82.9: 21.67		TNPO2_HUMAN (33-1045): 7.78e-129: 415: 14.41
+	Hs
		155639 Q9H4D1_HUMAN (403-500): 4.98e-15: 79.8: 23.47		TNPO2_HUMAN (33-1045): 7.78e-129: 415: 14.41
+	Hs
		207918 RIPK4_HUMAN (381-500): 5.47e-16: 82.9: 21.67		XPOT_HUMAN (29-1023): 3.55e-126: 410: 14.85