HitPredict

Interactor 1: IKBE (O00221)
NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkB-E) (IkB-epsilon) (IkappaBepsilon)
Gene: NFKBIE

Interactor 2: PP6R2 (O75170)
Serine/threonine-protein phosphatase 6 regulatory subunit 2 (SAPS domain family member 2)
Gene: PPP6R2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	14743216, 16769727
Identification Methods	tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 500 Hs			1 966
+	Hs
		166864 ANR28_HUMAN (30-458): 1.63e-51: 190: 15.28		PP6R2_HUMAN (1-966): 0: 893: 100.00
+	Hs
		257199 ANR44_HUMAN (16-364): 1.76e-36: 146: 12.50		PP6R2_HUMAN (1-966): 0: 893: 100.00
+	Hs
		257200 ANR52_HUMAN (298-488): 3.21e-13: 74.3: 33.85		PP6R2_HUMAN (1-966): 0: 893: 100.00
+	Hs
		166945 ANR28_HUMAN (30-458): 1.63e-51: 190: 15.28		PP6R3_HUMAN (1-914): 0: 746: 46.31
+	Hs
		1126010 ANR44_HUMAN (16-364): 1.76e-36: 146: 12.50		PP6R3_HUMAN (1-914): 0: 746: 46.31
+	Hs
		167044 ANR28_HUMAN (30-458): 1.63e-51: 190: 15.28		PP6R1_HUMAN (1-898): 0: 640: 39.94
+	Hs
		121590 IKBE_HUMAN (405-499): 6.48e-15: 79.1: 22.86		PP6R3_HUMAN (1-914): 0: 746: 46.31
+	Hs
		1126012 ANR52_HUMAN (298-488): 3.21e-13: 74.3: 33.85		PP6R3_HUMAN (1-914): 0: 746: 46.31
+	Hs
		1237562 ANR44_HUMAN (16-364): 1.76e-36: 146: 12.50		PP6R1_HUMAN (1-898): 0: 640: 39.94
+	Hs
		883672 RIPK4_HUMAN (381-500): 5.47e-16: 82.9: 21.67		PP6R1_HUMAN (1-898): 0: 640: 39.94
+	Hs
		1330883 Q9H4D1_HUMAN (403-500): 4.98e-15: 79.8: 23.47		PP6R1_HUMAN (1-898): 0: 640: 39.94
+	Hs
		121602 IKBE_HUMAN (405-499): 6.48e-15: 79.1: 22.86		PP6R1_HUMAN (1-898): 0: 640: 39.94
+	Hs
		1239519 ANR52_HUMAN (298-488): 3.21e-13: 74.3: 33.85		PP6R1_HUMAN (1-898): 0: 640: 39.94
+	Hs
		1144659 ASB3_HUMAN (199-468): 5.42e-32: 130: 16.55		TENS2_HUMAN (596-922): 8.28e-17: 88.1: 13.15
+	Hs
		883550 RIPK4_HUMAN (381-500): 5.47e-16: 82.9: 21.67		HUWE1_HUMAN (487-954): 7.07e-26: 118: 13.22
+	Hs
		1192213 Q9H4D1_HUMAN (403-500): 4.98e-15: 79.8: 23.47		HUWE1_HUMAN (487-954): 7.07e-26: 118: 13.22
+	Hs
		310061 TNKS1_HUMAN (6-279): 3.79e-24: 108: 10.58		TENS2_HUMAN (596-922): 8.28e-17: 88.1: 13.15