HitPredict

Interactor 1: IKBE (O00221)
NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkB-E) (IkB-epsilon) (IkappaBepsilon)
Gene: NFKBIE

Interactor 2: TBB4A (P04350)
Tubulin beta-4A chain (Tubulin 5 beta) (Tubulin beta-4 chain)
Gene: TUBB4A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	14743216
Identification Methods	tandem affinity purification
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ank_2~Tubulin
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 500 Hs			1 444
+	Hs
		428145 ANK2_HUMAN (162-497): 6.94e-75: 259: 19.01		TBB5_HUMAN (1-429): 0: 714: 97.44
+	Hs
		965103 ANK2_HUMAN (162-497): 6.94e-75: 259: 19.01		TBB2A_HUMAN (1-430): 0: 709: 96.28
+	Hs
		428225 IKBB_HUMAN (254-447): 4.47e-26: 110: 37.50		TBB5_HUMAN (1-429): 0: 714: 97.44
+	Hs
		862023 DAPK1_HUMAN (4-284): 1.05e-20: 97.9: 10.68		TBB4B_HUMAN (1-427): 0: 713: 98.60
+	Hs
		428113 RIPK4_HUMAN (381-500): 5.47e-16: 82.9: 21.67		TBB5_HUMAN (1-429): 0: 714: 97.44
+	Hs
		883508 RIPK4_HUMAN (381-500): 5.47e-16: 82.9: 21.67		TBB3_HUMAN (1-444): 0: 714: 91.44
+	Hs
		883476 RIPK4_HUMAN (381-500): 5.47e-16: 82.9: 21.67		TBB4B_HUMAN (1-427): 0: 713: 98.60
+	Hs
		883632 RIPK4_HUMAN (381-500): 5.47e-16: 82.9: 21.67		TBB2B_HUMAN (1-430): 0: 712: 96.74
+	Hs
		1037393 Q9H4D1_HUMAN (403-500): 4.98e-15: 79.8: 23.47		TBB3_HUMAN (1-444): 0: 714: 91.44
+	Hs
		428431 Q9H4D1_HUMAN (403-500): 4.98e-15: 79.8: 23.47		TBB5_HUMAN (1-429): 0: 714: 97.44
+	Hs
		121557 IKBE_HUMAN (405-499): 6.48e-15: 79.1: 22.86		TBB5_HUMAN (1-429): 0: 714: 97.44
+	Hs
		933974 Q9H4D1_HUMAN (403-500): 4.98e-15: 79.8: 23.47		TBB4B_HUMAN (1-427): 0: 713: 98.60
+	Hs
		381154 RIPK4_HUMAN (381-500): 5.47e-16: 82.9: 21.67		TBB4A_HUMAN (1-427): 0: 709: 100.00
+	Hs
		883510 RIPK4_HUMAN (381-500): 5.47e-16: 82.9: 21.67		TBB2A_HUMAN (1-430): 0: 709: 96.28
+	Hs
		1313672 Q9H4D1_HUMAN (403-500): 4.98e-15: 79.8: 23.47		TBB2B_HUMAN (1-430): 0: 712: 96.74
+	Hs
		883630 RIPK4_HUMAN (381-500): 5.47e-16: 82.9: 21.67		TBB6_HUMAN (1-433): 0: 708: 93.07
+	Hs
		1046578 Q9H4D1_HUMAN (403-500): 4.98e-15: 79.8: 23.47		TBB2A_HUMAN (1-430): 0: 709: 96.28
+	Hs
		381300 Q9H4D1_HUMAN (403-500): 4.98e-15: 79.8: 23.47		TBB4A_HUMAN (1-427): 0: 709: 100.00
+	Hs
		1312810 Q9H4D1_HUMAN (403-500): 4.98e-15: 79.8: 23.47		TBB6_HUMAN (1-433): 0: 708: 93.07
+	Dm
		1098153 NFKB1_DROME (260-444): 2.67e-13: 74.7: 29.80		TBB1_DROME (1-429): 0: 711: 96.27