HitPredict

Interactor 1: CASP8 (Q8IRY7)
Caspase-8 (EC 3.4.22.61) (Death-related ced-3/NEDD2-like protein) [Cleaved into: Caspase-8 subunit p15; Caspase-8 subunit p10]
Gene: Dredd

Interactor 2: CASP8 (Q8IRY7)
Caspase-8 (EC 3.4.22.61) (Death-related ced-3/NEDD2-like protein) [Cleaved into: Caspase-8 subunit p15; Caspase-8 subunit p10]
Gene: Dredd

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.69 1.00 0.834

The method score is based on:

Property Details
Experiments 24891502, 22549468, 23749869
Identification Methods enzymatic study, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Peptidase_C14~Peptidase_C14
Common GO terms GO:0002230 - positive regulation of defense response to virus by host
GO:0004175 - endopeptidase activity
GO:0004197 - cysteine-type endopeptidase activity
GO:0005737 - cytoplasm
GO:0005829 - cytosol
and 19 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 494
Dm

1 494
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024