HitPredict

Interactor 1: IKBE (O00221)
NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkB-E) (IkB-epsilon) (IkappaBepsilon)
Gene: NFKBIE

Interactor 2: HS71L (P34931)
Heat shock 70 kDa protein 1-like (Heat shock 70 kDa protein 1L) (Heat shock 70 kDa protein 1-Hom) (HSP70-Hom) (Heat shock protein family A member 1L)
Gene: HSPA1L

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	14743216
Identification Methods	tandem affinity purification
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 500 Hs			1 641
+	Hs
		503916 ANK2_HUMAN (162-497): 6.94e-75: 259: 19.01		HSP7C_HUMAN (4-615): 0: 946: 84.80
+	Hs
		483759 ANK2_HUMAN (162-497): 6.94e-75: 259: 19.01		HS71A_HUMAN (1-641): 0: 938: 88.80
+	Hs
		564002 BCL3_HUMAN (145-486): 2.53e-73: 240: 32.49		HSP76_HUMAN (1-641): 0: 957: 79.47
+	Hs
		714021 ANKK1_HUMAN (1-330): 1.67e-29: 124: 10.00		HS71L_HUMAN (1-641): 0: 977: 100.00
+	Dr
		1157472 MIB1_DANRE (272-500): 2.6e-40: 157: 21.74		Q6NYR4_DANRE (4-616): 0: 939: 85.48
+	Hs
		713979 IKBB_HUMAN (254-447): 4.47e-26: 110: 37.50		HS71L_HUMAN (1-641): 0: 977: 100.00
+	Hs
		504130 IKBB_HUMAN (254-447): 4.47e-26: 110: 37.50		HSP7C_HUMAN (4-615): 0: 946: 84.80
+	Hs
		587444 NFKB1_HUMAN (386-481): 8.64e-13: 72.8: 24.51		HS71L_HUMAN (1-641): 0: 977: 100.00
+	Hs
		639682 IKBA_HUMAN (252-330): 1.11e-12: 70.9: 30.00		HS71L_HUMAN (1-641): 0: 977: 100.00
+	Hs
		564048 RIPK4_HUMAN (381-500): 5.47e-16: 82.9: 21.67		HSP76_HUMAN (1-641): 0: 957: 79.47
+	Hs
		564185 Q9H4D1_HUMAN (403-500): 4.98e-15: 79.8: 23.47		HSP76_HUMAN (1-641): 0: 957: 79.47
+	Hs
		564000 NFKB1_HUMAN (386-481): 8.64e-13: 72.8: 24.51		HSP76_HUMAN (1-641): 0: 957: 79.47
+	Hs
		503777 RIPK4_HUMAN (381-500): 5.47e-16: 82.9: 21.67		HSP7C_HUMAN (4-615): 0: 946: 84.80
+	Hs
		504758 Q9H4D1_HUMAN (403-500): 4.98e-15: 79.8: 23.47		HSP7C_HUMAN (4-615): 0: 946: 84.80
+	Hs
		121564 IKBE_HUMAN (405-499): 6.48e-15: 79.1: 22.86		HSP7C_HUMAN (4-615): 0: 946: 84.80
+	Hs
		503415 NFKB1_HUMAN (386-481): 8.64e-13: 72.8: 24.51		HSP7C_HUMAN (4-615): 0: 946: 84.80
+	Hs
		503471 IKBA_HUMAN (252-330): 1.11e-12: 70.9: 30.00		HSP7C_HUMAN (4-615): 0: 946: 84.80
+	Mm
		638457 NFKB1_MOUSE (386-481): 1.38e-12: 72.4: 23.53		HS71A_MOUSE (4-641): 0: 943: 87.66
+	Hs
		587480 NFKB1_HUMAN (386-481): 8.64e-13: 72.8: 24.51		HSP72_HUMAN (3-641): 0: 934: 81.90
+	Dm
		505074 NFKB1_DROME (260-444): 2.67e-13: 74.7: 29.80		HSP7D_DROME (4-614): 0: 928: 82.49