HitPredict

Interactor 1: IFNL1 (Q8IU54)
Interferon lambda-1 (IFN-lambda-1) (Cytokine Zcyto21) (Interleukin-29) (IL-29)
Gene: IFNL1

Interactor 2: IRF7 (Q92985)
Interferon regulatory factor 7 (IRF-7)
Gene: IRF7

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	17785777, 21398614
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0045087 - innate immune response GO:0045893 - positive regulation of DNA-templated transcription GO:0051607 - defense response to virus
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 200 Hs			1 503
+	Hs
		1224458 IFNL3_HUMAN (1-191): 5.14e-117: 331: 71.94		IRF7_HUMAN (1-503): 0: 530: 100.00
+	Hs
		971740 IFNL1_HUMAN (1-200): 1.33e-123: 348: 100.00		IRF8_HUMAN (12-485): 3.83e-123: 368: 21.04
+	Hs
		971741 IFNL3_HUMAN (1-191): 5.14e-117: 331: 71.94		IRF8_HUMAN (12-485): 3.83e-123: 368: 21.04
+	Hs
		501063 IFNL1_HUMAN (1-200): 1.33e-123: 348: 100.00		IRF1_HUMAN (8-276): 4.24e-71: 230: 19.00
+	Hs
		501067 IFNL3_HUMAN (1-191): 5.14e-117: 331: 71.94		IRF1_HUMAN (8-276): 4.24e-71: 230: 19.00
+	Hs
		1056433 IFNL1_HUMAN (1-200): 1.33e-123: 348: 100.00		IRF3_HUMAN (6-263): 1.1e-60: 207: 25.66
+	Hs
		1056436 IFNL3_HUMAN (1-191): 5.14e-117: 331: 71.94		IRF3_HUMAN (6-263): 1.1e-60: 207: 25.66