Interactor 1: IKBE (O00221)
NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkB-E) (IkB-epsilon) (IkappaBepsilon)
Gene: NFKBIE
Interactor 2: TF65 (Q04206)
Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3)
Gene: RELA
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.94 | 1.00 | 0.973 |
The method score is based on:
Property | Details |
---|---|
Experiments | 29084252, 27609421, 35271311, 9315679, 21988832, 14743216, 9135156, 15722553 |
Identification Methods | affinity chromatography technology, two hybrid, pull down, tandem affinity purification, anti tag coimmunoprecipitation, electrophoretic mobility supershift assay, two hybrid array |
Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | Ank_2~RHD_dimer |
Common GO terms | GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0051059 - NF-kappaB binding GO:0071356 - cellular response to tumor necrosis factor |
Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024