Interactor 1: IKBE (O00221)
NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkB-E) (IkB-epsilon) (IkappaBepsilon)
Gene: NFKBIE

Interactor 2: TF65 (Q04206)
Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3)
Gene: RELA

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.973

The method score is based on:

Property Details
Experiments 29084252, 27609421, 35271311, 9315679, 21988832, 14743216, 9135156, 15722553
Identification Methods affinity chromatography technology, two hybrid, pull down, tandem affinity purification, anti tag coimmunoprecipitation, electrophoretic mobility supershift assay, two hybrid array
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Ank_2~RHD_dimer
Common GO terms GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0051059 - NF-kappaB binding
GO:0071356 - cellular response to tumor necrosis factor
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 500
Hs

1 551
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024