Interactor 1: DCP2 (Q8IU60)
m7GpppN-mRNA hydrolase (EC 3.6.1.62) (Nucleoside diphosphate-linked moiety X motif 20) (Nudix motif 20) (mRNA-decapping enzyme 2) (hDpc)
Gene: DCP2
Interactor 2: DCP1A (Q9NPI6)
mRNA-decapping enzyme 1A (EC 3.6.1.62) (Smad4-interacting transcriptional co-activator) (Transcription factor SMIF)
Gene: DCP1A
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.97 | 1.00 | 0.986 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 26186194, 28514442, 12417715, 33961781, 16364915, 15231747, 24778252, 26496610, 27315556, 29395067, 25036637, 19966221, 23085078, 24510189 |
| Identification Methods | affinity chromatography technology, pull down, two hybrid, proximity labelling technology, anti tag coimmunoprecipitation |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | DCP1~DCP2, DCP1~NUDIX |
| Common GO terms | GO:0000184 - nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000290 - deadenylation-dependent decapping of nuclear-transcribed mRNA GO:0000932 - P-body GO:0005737 - cytoplasm GO:0005829 - cytosol and 2 others more... |
| Homologous interactions | 3 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
