Interactor 1: TMPS6 (Q8IU80)
Transmembrane protease serine 6 (EC 3.4.21.-) (Matriptase-2)
Gene: TMPRSS6

Interactor 2: KLK6 (Q92876)
Kallikrein-6 (EC 3.4.21.-) (Neurosin) (Protease M) (SP59) (Serine protease 18) (Serine protease 9) (Zyme)
Gene: KLK6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.44 1.00 0.665

The method score is based on:

Property Details
Experiments 32814053
Identification Methods two hybrid array, two hybrid pooling approach, validated two hybrid
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Ldl_recept_a~Trypsin, Trypsin~Trypsin
Common GO terms GO:0004252 - serine-type endopeptidase activity
GO:0005615 - extracellular space
GO:0030574 - collagen catabolic process
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 811
Hs

1 244
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024