HitPredict

Interactor 1: I2BP1 (Q8IU81)
Interferon regulatory factor 2-binding protein 1 (IRF-2-binding protein 1) (IRF-2BP1) (Probable E3 ubiquitin-protein ligase IRF2BP1) (EC 2.3.2.27) (Probable RING-type E3 ubiquitin transferase IRF2BP1)
Gene: IRF2BP1

Interactor 2: I2BPL (Q9H1B7)
Probable E3 ubiquitin-protein ligase IRF2BPL (EC 2.3.2.27) (Enhanced at puberty protein 1) (Interferon regulatory factor 2-binding protein-like)
Gene: IRF2BPL

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.74 0.60 0.667

The method score is based on:

Property Details
Experiments 21444724, 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0003714 - transcription corepressor activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0046872 - metal ion binding
and 1 others

more...
Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 584
Hs

1 796
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Ce
+ Ce

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024