HitPredict

Interactor 1: CERS3 (Q8IU89)
Ceramide synthase 3 (CerS3) (Dihydroceramide synthase 3) (LAG1 longevity assurance homolog 3) (Sphingosine N-acyltransferase CERS3) (EC 2.3.1.24) (Ultra-long-chain ceramide synthase CERS3) (EC 2.3.1.298) (Very-long-chain ceramide synthase CERS3) (EC 2.3.1.297)
Gene: CERS3

Interactor 2: I36RA (Q9UBH0)
Interleukin-36 receptor antagonist protein (IL-36Ra) (FIL1 delta) (IL-1-related protein 3) (IL-1RP3) (Interleukin-1 HY1) (IL-1HY1) (Interleukin-1 delta) (IL-1 delta) (Interleukin-1 family member 5) (IL-1F5) (Interleukin-1 receptor antagonist homolog 1) (IL-1ra homolog 1) (Interleukin-1-like protein 1) (IL-1L1)
Gene: IL36RN

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1 383 Hs			1 155
+	Hs
		1215942 CERS3_HUMAN (1-383): 1.64e-136: 396: 100.00		IL36G_HUMAN (11-142): 1.71e-48: 155: 33.09
+	Hs
		1215945 CERS3_HUMAN (1-383): 1.64e-136: 396: 100.00		IL36A_HUMAN (10-149): 3.5e-43: 141: 34.48