HitPredict

Interactor 1: IKBE (O00221)
NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkB-E) (IkB-epsilon) (IkappaBepsilon)
Gene: NFKBIE

Interactor 2: PP6R1 (Q9UPN7)
Serine/threonine-protein phosphatase 6 regulatory subunit 1 (SAPS domain family member 1)
Gene: PPP6R1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	14743216, 16769727
Identification Methods	tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 500 Hs			1 881
+	Hs
		167044 ANR28_HUMAN (30-458): 1.63e-51: 190: 15.28		PP6R1_HUMAN (1-881): 0: 828: 100.00
+	Hs
		166864 ANR28_HUMAN (30-458): 1.63e-51: 190: 15.28		PP6R2_HUMAN (1-880): 0: 793: 40.08
+	Hs
		1237562 ANR44_HUMAN (16-364): 1.76e-36: 146: 12.50		PP6R1_HUMAN (1-881): 0: 828: 100.00
+	Hs
		166945 ANR28_HUMAN (30-458): 1.63e-51: 190: 15.28		PP6R3_HUMAN (1-876): 0: 766: 43.85
+	Hs
		257199 ANR44_HUMAN (16-364): 1.76e-36: 146: 12.50		PP6R2_HUMAN (1-880): 0: 793: 40.08
+	Hs
		1126010 ANR44_HUMAN (16-364): 1.76e-36: 146: 12.50		PP6R3_HUMAN (1-876): 0: 766: 43.85
+	Hs
		883672 RIPK4_HUMAN (381-500): 5.47e-16: 82.9: 21.67		PP6R1_HUMAN (1-881): 0: 828: 100.00
+	Hs
		1330883 Q9H4D1_HUMAN (403-500): 4.98e-15: 79.8: 23.47		PP6R1_HUMAN (1-881): 0: 828: 100.00
+	Hs
		1239519 ANR52_HUMAN (298-488): 3.21e-13: 74.3: 33.85		PP6R1_HUMAN (1-881): 0: 828: 100.00
+	Hs
		121552 IKBE_HUMAN (405-499): 6.48e-15: 79.1: 22.86		PP6R2_HUMAN (1-880): 0: 793: 40.08
+	Hs
		257200 ANR52_HUMAN (298-488): 3.21e-13: 74.3: 33.85		PP6R2_HUMAN (1-880): 0: 793: 40.08
+	Hs
		121590 IKBE_HUMAN (405-499): 6.48e-15: 79.1: 22.86		PP6R3_HUMAN (1-876): 0: 766: 43.85
+	Hs
		1126012 ANR52_HUMAN (298-488): 3.21e-13: 74.3: 33.85		PP6R3_HUMAN (1-876): 0: 766: 43.85
+	Hs
		965156 ANK2_HUMAN (162-497): 6.94e-75: 259: 19.01		UBP42_HUMAN (468-864): 1.5e-31: 135: 12.11