HitPredict

Interactor 1: CILP2 (Q8IUL8)
Cartilage intermediate layer protein 2 (CILP-2) [Cleaved into: Cartilage intermediate layer protein 2 C1; Cartilage intermediate layer protein 2 C2]
Gene: CILP2

Interactor 2: VWCE (Q96DN2)
von Willebrand factor C and EGF domain-containing protein (HBV X protein up-regulated gene 11 protein) (HBxAg up-regulated gene 11 protein)
Gene: VWCE

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.50	0.574

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1156 Hs			1 955
+	Hs
		980436 CILP2_HUMAN (14-1156): 0: 1560: 100.00		NOTC2_HUMAN (224-849): 3.36e-38: 157: 12.27
+	Hs
		1216637 CILP2_HUMAN (14-1156): 0: 1560: 100.00		FBLN5_HUMAN (61-281): 2.58e-37: 148: 30.21
+	Hs
		314794 CILP2_HUMAN (14-1156): 0: 1560: 100.00		MATN4_HUMAN (49-218): 1.33e-23: 108: 25.29
+	Hs
		980569 ATS1_HUMAN (14-289): 6.32e-49: 191: 20.92		NOTC2_HUMAN (224-849): 3.36e-38: 157: 12.27
+	Hs
		980469 ATS15_HUMAN (71-289): 4.19e-43: 172: 20.25		NOTC2_HUMAN (224-849): 3.36e-38: 157: 12.27
+	Hs
		254302 ATS1_HUMAN (14-289): 6.32e-49: 191: 20.92		LRP4_HUMAN (69-233): 5.88e-09: 62.5: 18.44
+	Hs
		980468 ATS17_HUMAN (40-287): 1.31e-15: 84.4: 14.49		NOTC2_HUMAN (224-849): 3.36e-38: 157: 12.27
+	Hs
		980561 ATS9_HUMAN (13-146): 1.06e-09: 65.1: 10.81		NOTC2_HUMAN (224-849): 3.36e-38: 157: 12.27
+	Hs
		434636 TSP1_HUMAN (2-281): 1.75e-21: 103: 11.84		JAG1_HUMAN (472-832): 1.91e-17: 90.2: 10.33
+	Hs
		1053518 ATS17_HUMAN (40-287): 1.31e-15: 84.4: 14.49		GAS6_HUMAN (155-305): 3.67e-21: 101: 25.48
+	Hs
		1204937 ATS17_HUMAN (40-287): 1.31e-15: 84.4: 14.49		FRAS1_HUMAN (4-653): 8.84e-21: 101: 11.67
+	Hs
		434623 TSP1_HUMAN (2-281): 1.75e-21: 103: 11.84		FBN2_HUMAN (3-483): 4.74e-15: 82.4: 12.34
+	Ce
		107288 ADT2_CAEEL (2-462): 3.31e-21: 102: 11.55		G5EF34_CAEEL (417-794): 1.19e-11: 71: 21.18
+	Ce
		104611 Q7Z291_CAEEL (2-366): 1.97e-20: 99.9: 10.42		G5EBZ2_CAEEL (462-794): 1.19e-11: 71: 23.41
+	Hs
		434622 TSP1_HUMAN (2-281): 1.75e-21: 103: 11.84		FBN1_HUMAN (125-262): 3.99e-09: 63.2: 37.67
+	Ce
		104604 Q22631_CAEEL (134-470): 7.29e-15: 81.8: 14.00		G5EBZ2_CAEEL (462-794): 1.19e-11: 71: 23.41
+	Ce
		107297 Q22631_CAEEL (134-470): 7.29e-15: 81.8: 14.00		G5EF34_CAEEL (417-794): 1.19e-11: 71: 21.18
+	Hs
		724382 ATL1_HUMAN (237-487): 4.17e-09: 63.3: 15.36		FBN2_HUMAN (3-483): 4.74e-15: 82.4: 12.34
+	Hs
		1167023 ATS13_HUMAN (122-202): 6.91e-10: 65.8: 35.29		FAT4_HUMAN (327-495): 6.02e-10: 65.8: 15.12