HitPredict

Interactor 1: PSD11 (O00231)
26S proteasome non-ATPase regulatory subunit 11 (26S proteasome regulatory subunit RPN6) (26S proteasome regulatory subunit S9) (26S proteasome regulatory subunit p44.5)
Gene: PSMD11

Interactor 2: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.69	0.60	0.646

Property	Details
Experiments	28190767, 33141564, 16196087
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 422 Hs			1 685
+	Hs
		475555 CSN2_HUMAN (8-419): 1.5e-88: 277: 22.80		UBC_HUMAN (1-685): 0: 846: 100.00
+	Hs
		475779 PSMD6_HUMAN (31-422): 3.57e-77: 246: 13.68		UBC_HUMAN (1-685): 0: 846: 100.00
+	Hs
		476293 CSN4_HUMAN (4-422): 5.53e-72: 233: 14.62		UBC_HUMAN (1-685): 0: 846: 100.00
+	Hs
		121918 PSD12_HUMAN (46-422): 1.57e-66: 220: 12.86		UBC_HUMAN (1-685): 0: 846: 100.00
+	Sc
		477496 RPN6_YEAST (39-421): 4.48e-81: 257: 45.36		UBI4P_YEAST (381-685): 5e-122: 370: 95.74
+	At
		1092149 PSD11_ARATH (10-421): 4.55e-96: 295: 51.94		UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63
+	Hs
		121730 PSD11_HUMAN (1-422): 1.54e-117: 351: 100.00		RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00
+	At
		1091885 PSMD6_ARATH (34-422): 8.51e-66: 216: 14.71		UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63
+	Mm
		476877 PSD11_MOUSE (1-422): 4.03e-117: 349: 99.76		UBC_MOUSE (1-108): 9.43e-30: 127: 90.74
+	At
		799469 CSN1_ARATH (70-421): 1.51e-57: 196: 16.13		UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63
+	Hs
		121663 PSD11_HUMAN (1-422): 1.54e-117: 351: 100.00		ISG15_HUMAN (228-380): 1.72e-28: 113: 32.69
+	Mm
		476740 CSN2_MOUSE (8-419): 1.5e-88: 277: 22.80		UBC_MOUSE (1-108): 9.43e-30: 127: 90.74
+	Rn
		897345 CSN2_RAT (8-419): 1.5e-88: 277: 22.80		UBC_RAT (1-108): 1.27e-29: 127: 90.74
+	Hs
		923997 PSMD6_HUMAN (31-422): 3.57e-77: 246: 13.68		RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00
+	Mm
		476962 PSMD6_MOUSE (31-422): 4.79e-76: 243: 13.68		UBC_MOUSE (1-108): 9.43e-30: 127: 90.74
+	Hs
		121987 PSD12_HUMAN (46-422): 1.57e-66: 220: 12.86		RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00
+	Mm
		291853 CSN4_MOUSE (4-422): 7.3e-72: 233: 14.62		UBC_MOUSE (1-108): 9.43e-30: 127: 90.74
+	Hs
		397972 PSMD6_HUMAN (31-422): 3.57e-77: 246: 13.68		ISG15_HUMAN (228-380): 1.72e-28: 113: 32.69
+	Mm
		477004 PSD12_MOUSE (46-422): 3.22e-65: 217: 12.86		UBC_MOUSE (1-108): 9.43e-30: 127: 90.74
+	Mm
		102344 G3UXW9_MOUSE (116-421): 2.25e-55: 193: 17.41		UBC_MOUSE (1-108): 9.43e-30: 127: 90.74