HitPredict

Interactor 1: PSD11 (O00231)
26S proteasome non-ATPase regulatory subunit 11 (26S proteasome regulatory subunit RPN6) (26S proteasome regulatory subunit S9) (26S proteasome regulatory subunit p44.5)
Gene: PSMD11

Interactor 2: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.643

Property	Details
Experiments	32812023, 26269332, 35063084
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 422 Hs			1 758
+	Hs
		496706 CSN2_HUMAN (8-419): 1.5e-88: 277: 22.80		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		497037 PSMD6_HUMAN (31-422): 3.57e-77: 246: 13.68		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		497525 CSN4_HUMAN (4-422): 5.53e-72: 233: 14.62		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		121920 PSD12_HUMAN (46-422): 1.57e-66: 220: 12.86		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Rn
		582015 CSN4_RAT (4-422): 1.23e-71: 232: 14.85		TAU_RAT (1-758): 4.86e-75: 260: 71.47
+	Rn
		94241 CSN4_RAT (4-422): 1.23e-71: 232: 14.85		F1LST4_RAT (1-757): 8.59e-75: 260: 71.56
+	Hs
		496946 CSN1_HUMAN (213-421): 8.68e-44: 161: 16.98		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00