HitPredict

Interactor 1: ARMC8 (Q8IUR7)
Armadillo repeat-containing protein 8
Gene: ARMC8

Interactor 2: RMD5B (Q96G75)
E3 ubiquitin-protein transferase RMND5B (EC 2.3.2.27) (Protein RMD5 homolog B)
Gene: RMND5B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	27173435, 29911972, 33961781
Identification Methods	affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0034657 - GID complex GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 673 Hs			1 393
+	Hs
		1216839 ARMC8_HUMAN (1-673): 3.83e-127: 393: 100.00		RMD5A_HUMAN (1-393): 1.67e-147: 424: 69.98
+	Hs
		1185113 ARMC8_HUMAN (1-673): 3.83e-127: 393: 100.00		MAEA_HUMAN (1-392): 3.27e-115: 342: 20.36
+	Hs
		1216846 ARMC8_HUMAN (1-673): 3.83e-127: 393: 100.00		GID8_HUMAN (96-320): 1.08e-42: 150: 17.03
+	Sc
		775423 VID28_YEAST (238-630): 4.53e-70: 247: 16.83		RMD5_YEAST (1-393): 3.43e-85: 267: 21.22
+	Hs
		1216812 ARMC8_HUMAN (1-673): 3.83e-127: 393: 100.00		RANB9_HUMAN (114-211): 2.85e-11: 67.1: 23.47
+	Sc
		774569 VID28_YEAST (238-630): 4.53e-70: 247: 16.83		FYV10_YEAST (7-253): 9.96e-40: 149: 15.58