HitPredict

Interactor 1: ARMC8 (Q8IUR7)
Armadillo repeat-containing protein 8
Gene: ARMC8

Interactor 2: PKP4 (Q99569)
Plakophilin-4 (p0071)
Gene: PKP4

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.806

Property	Details
Experiments	30482882, 33961781
Identification Methods	two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	Arm~Arm
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 673 Hs			1 1192
+	Mm
		1148451 SPAG6_MOUSE (61-298): 8.17e-13: 73.2: 19.25		PKP4_MOUSE (1-1192): 0: 1131: 96.48
+	Hs
		1216819 ARMC8_HUMAN (1-673): 3.83e-127: 393: 100.00		PKP2_HUMAN (156-1014): 1.57e-160: 502: 24.78
+	Hs
		1216869 ARMC8_HUMAN (1-673): 3.83e-127: 393: 100.00		PKP3_HUMAN (218-1014): 2.04e-152: 478: 26.92
+	Hs
		717200 ARMC8_HUMAN (1-673): 3.83e-127: 393: 100.00		CTNB1_HUMAN (311-1123): 4.61e-149: 469: 16.00
+	Hs
		1045974 ARMC8_HUMAN (1-673): 3.83e-127: 393: 100.00		PKP1_HUMAN (413-1009): 2.18e-124: 402: 28.59
+	Hs
		238678 IMA7_HUMAN (152-547): 2.32e-34: 139: 13.22		TRIPC_HUMAN (110-1126): 7.22e-126: 429: 11.99
+	Hs
		168635 IMA6_HUMAN (389-673): 1.01e-32: 134: 17.30		TRIPC_HUMAN (110-1126): 7.22e-126: 429: 11.99
+	Hs
		853599 IMA5_HUMAN (152-547): 6.76e-28: 120: 13.22		TRIPC_HUMAN (110-1126): 7.22e-126: 429: 11.99