HitPredict

Interactor 1: MEX3C (Q5U5Q3)
RNA-binding E3 ubiquitin-protein ligase MEX3C (EC 2.3.2.27) (RING finger and KH domain-containing protein 2) (RING finger protein 194) (RING-type E3 ubiquitin transferase MEX3C)
Gene: MEX3C

Interactor 2: UBP7 (Q93009)
Ubiquitin carboxyl-terminal hydrolase 7 (EC 3.4.19.12) (Deubiquitinating enzyme 7) (Herpesvirus-associated ubiquitin-specific protease) (Ubiquitin thioesterase 7) (Ubiquitin-specific-processing protease 7)
Gene: USP7

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.534

Property	Details
Experiments	22863774
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 659 Hs			1 1102
+	Hs
		1252359 MEX3B_HUMAN (226-659): 5.5e-166: 488: 54.31		UBP7_HUMAN (1-1102): 0: 1183: 100.00
+	Hs
		85198 MEX3C_HUMAN (1-659): 0: 698: 100.00		B7Z7T5_HUMAN (100-897): 0: 822: 99.50
+	Hs
		1107083 BIRC3_HUMAN (606-658): 8.32e-12: 70.2: 26.42		UBP7_HUMAN (1-1102): 0: 1183: 100.00
+	Hs
		1107445 BIRC2_HUMAN (586-658): 1e-11: 69.9: 23.29		UBP7_HUMAN (1-1102): 0: 1183: 100.00
+	Mm
		59874 BIRC7_MOUSE (431-658): 7.75e-14: 74.5: 14.47		UBP7_MOUSE (1-1102): 0: 1178: 99.00
+	Hs
		1361990 RFFL_HUMAN (579-658): 3.07e-11: 67.5: 22.50		UBP7_HUMAN (1-1102): 0: 1183: 100.00
+	Hs
		1217008 MEX3C_HUMAN (1-659): 0: 698: 100.00		USP9X_HUMAN (173-554): 3.63e-96: 339: 23.49
+	Hs
		1107082 BIRC3_HUMAN (606-658): 8.32e-12: 70.2: 26.42		USP9X_HUMAN (173-554): 3.63e-96: 339: 23.49
+	Hs
		1107444 BIRC2_HUMAN (586-658): 1e-11: 69.9: 23.29		USP9X_HUMAN (173-554): 3.63e-96: 339: 23.49