HitPredict

Interactor 1: NUDC3 (Q8IVD9)
NudC domain-containing protein 3
Gene: NUDCD3

Interactor 2: KLD8A (Q8IYD2)
Kelch domain-containing protein 8A (Substitute for delta-EGFR expression 1) (S-delta-E1)
Gene: KLHDC8A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.50	0.609

Property	Details
Experiments	28514442, 33961781, 25036637
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, luminescence based mammalian interactome mapping
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 361 Hs			1 350
+	Hs
		1217438 NUDC3_HUMAN (1-361): 2.02e-159: 452: 100.00		KLHL1_HUMAN (1-277): 1.69e-78: 256: 22.62
+	Hs
		1217464 NUDC3_HUMAN (1-361): 2.02e-159: 452: 100.00		KLH20_HUMAN (63-350): 1.33e-77: 251: 22.34
+	Hs
		299523 NUDC3_HUMAN (1-361): 2.02e-159: 452: 100.00		KLH18_HUMAN (1-261): 8.72e-73: 237: 25.29
+	Hs
		1049257 NUDC3_HUMAN (1-361): 2.02e-159: 452: 100.00		KEAP1_HUMAN (77-349): 5.01e-71: 234: 21.30
+	Hs
		1217455 NUDC3_HUMAN (1-361): 2.02e-159: 452: 100.00		KLHL3_HUMAN (123-350): 1.54e-53: 187: 21.30
+	Hs
		1120783 NUDC3_HUMAN (1-361): 2.02e-159: 452: 100.00		KLH12_HUMAN (108-349): 4.12e-53: 185: 20.33
+	Hs
		307194 NUDC3_HUMAN (1-361): 2.02e-159: 452: 100.00		KLHL2_HUMAN (129-350): 1.52e-51: 182: 21.43
+	Hs
		1217446 NUDC3_HUMAN (1-361): 2.02e-159: 452: 100.00		KLH28_HUMAN (113-350): 2.6e-51: 180: 21.34
+	Hs
		1153785 NUDC3_HUMAN (1-361): 2.02e-159: 452: 100.00		KLH10_HUMAN (129-350): 4.15e-48: 172: 23.66
+	Hs
		1222997 NUDC_HUMAN (7-343): 2.07e-102: 306: 27.38		KLD8A_HUMAN (1-350): 8.88e-105: 312: 100.00
+	Hs
		1217431 NUDC3_HUMAN (1-361): 2.02e-159: 452: 100.00		KLHL4_HUMAN (131-350): 1.02e-40: 153: 20.36
+	Hs
		1122075 NUDC3_HUMAN (1-361): 2.02e-159: 452: 100.00		Q53XS2_HUMAN (15-255): 6.54e-21: 95.5: 30.68
+	Hs
		152493 NUDC3_HUMAN (1-361): 2.02e-159: 452: 100.00		ENC1_HUMAN (15-255): 6.54e-21: 95.5: 30.68
+	Hs
		1217433 NUDC3_HUMAN (1-361): 2.02e-159: 452: 100.00		KLH25_HUMAN (15-255): 2.4e-20: 94: 29.08
+	Hs
		1217452 NUDC3_HUMAN (1-361): 2.02e-159: 452: 100.00		KLH13_HUMAN (223-350): 3.45e-20: 93.8: 24.06
+	Hs
		1217450 NUDC3_HUMAN (1-361): 2.02e-159: 452: 100.00		KLHL9_HUMAN (223-350): 3.26e-19: 90.7: 23.31
+	Hs
		1217419 NUDC3_HUMAN (1-361): 2.02e-159: 452: 100.00		KLH29_HUMAN (54-334): 6.39e-10: 62.4: 26.80
+	Hs
		1261421 NUDC2_HUMAN (191-344): 9.87e-31: 116: 19.11		KLHL1_HUMAN (1-277): 1.69e-78: 256: 22.62
+	Hs
		1120805 NUDC1_HUMAN (155-282): 4.12e-26: 111: 20.93		KLH12_HUMAN (108-349): 4.12e-53: 185: 20.33
+	Hs
		1261414 NUDC2_HUMAN (191-344): 9.87e-31: 116: 19.11		KLHL4_HUMAN (131-350): 1.02e-40: 153: 20.36