Interactor 1: PSD11 (O00231)
26S proteasome non-ATPase regulatory subunit 11 (26S proteasome regulatory subunit RPN6) (26S proteasome regulatory subunit S9) (26S proteasome regulatory subunit p44.5)
Gene: PSMD11

Interactor 2: PSMD6 (Q15008)
26S proteasome non-ATPase regulatory subunit 6 (26S proteasome regulatory subunit RPN7) (26S proteasome regulatory subunit S10) (Breast cancer-associated protein SGA-113M) (Phosphonoformate immuno-associated protein 4) (Proteasome regulatory particle subunit p44S10) (p42A)
Gene: PSMD6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.86 1.00 0.929

The method score is based on:

Property Details
Experiments 17353931, 35271311, 28292943, 35235311, 37071682
Identification Methods affinity chromatography technology, pull down, cross-linking study, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains PCI~PCI, PCI~RPN7
Common GO terms GO:0000502 - proteasome complex
GO:0005576 - extracellular region
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0022624 - proteasome accessory complex
and 3 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 422
Hs

1 389
+ Dm
+ Hs
+ Dm
+ Hs
+ At
+ Mm
+ Sp
+ Hs
+ At
+ Hs
+ Zm
+ Dm
+ At
+ Sc
+ Hs
+ An
+ An
+ Sc

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Last updated: 15 Jul 2024