Interactor 1: APLF (Q8IW19)
Aprataxin and PNK-like factor (EC 3.1.-.-) (Apurinic-apyrimidinic endonuclease APLF) (PNK and APTX-like FHA domain-containing protein) (XRCC1-interacting protein 1)
Gene: APLF

Interactor 2: PARP2 (Q9UGN5)
Poly [ADP-ribose] polymerase 2 (PARP-2) (hPARP-2) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 2) (ARTD2) (DNA ADP-ribosyltransferase PARP2) (EC 2.4.2.-) (NAD(+) ADP-ribosyltransferase 2) (ADPRT-2) (Poly[ADP-ribose] synthase 2) (pADPRT-2) (Protein poly-ADP-ribosyltransferase PARP2) (EC 2.4.2.-)
Gene: PARP2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.80 0.60 0.696

The method score is based on:

Property Details
Experiments 26186194, 28514442, 33961781, 21812934
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, protein array
Interaction Type physical association, association, adp ribosylation reaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006281 - DNA repair
GO:0006302 - double-strand break repair
GO:0006974 - DNA damage response
and 3 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 511
Hs

1 583
+ Hs
+ Hs

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Last updated: 15 Jul 2024