Interactor 1: CDKAL (Q5VV42)
Threonylcarbamoyladenosine tRNA methylthiotransferase (EC 2.8.4.5) (CDK5 regulatory subunit-associated protein 1-like 1) (tRNA-t(6)A37 methylthiotransferase)
Gene: CDKAL1
Interactor 2: TYW1B (Q6NUM6)
S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1B (EC 4.1.3.44) (Radical S-adenosyl methionine and flavodoxin domain-containing protein 2) (tRNA wybutosine-synthesizing protein 1 homolog B)
Gene: TYW1B
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.47 | 0.90 | 0.656 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 28514442 |
| Identification Methods | affinity chromatography technology, anti tag coimmunoprecipitation |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Radical_SAM~Radical_SAM, Radical_SAM~Wyosine_form, Radical_SAM~TRAM, Radical_SAM~UPF0004 |
| Common GO terms | GO:0046872 - metal ion binding GO:0051539 - 4 iron, 4 sulfur cluster binding |
| Homologous interactions | 0 |
Service provided by Combinatics, Japan
Last updated: 11Aug2025
