HitPredict

Interactor 1: MGAP (Q8IWI9)
MAX gene-associated protein (MAX dimerization protein 5)
Gene: MGA

Interactor 2: RING2 (Q99496)
E3 ubiquitin-protein ligase RING2 (EC 2.3.2.27) (Huntingtin-interacting protein 2-interacting protein 3) (HIP2-interacting protein 3) (Protein DinG) (RING finger protein 1B) (RING1b) (RING finger protein 2) (RING finger protein BAP-1) (RING-type E3 ubiquitin transferase RING2)
Gene: RNF2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.89	0.60	0.733

Property	Details
Experiments	24457600, 26496610, 27705803, 24981860, 35933409, 22325352
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0071339 - MLL1 complex
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 3065 Hs			1 336
+	Hs
		987987 MGAP_HUMAN (1-3065): 0: 5622: 100.00		RING1_HUMAN (6-336): 8.6e-69: 222: 51.24
+	Hs
		1218715 MGAP_HUMAN (1-3065): 0: 5622: 100.00		PCGF1_HUMAN (28-336): 1.84e-47: 162: 16.88
+	Hs
		717992 MGAP_HUMAN (1-3065): 0: 5622: 100.00		BMI1_HUMAN (34-332): 4.13e-45: 158: 15.51
+	Hs
		718407 MGAP_HUMAN (1-3065): 0: 5622: 100.00		PCGF2_HUMAN (34-332): 8.08e-44: 155: 16.89
+	Hs
		1108514 MGAP_HUMAN (1-3065): 0: 5622: 100.00		PCGF3_HUMAN (36-334): 3.56e-44: 153: 18.15
+	Hs
		1218718 MGAP_HUMAN (1-3065): 0: 5622: 100.00		PCGF6_HUMAN (29-296): 6.61e-39: 142: 14.76
+	Hs
		1197567 MGAP_HUMAN (1-3065): 0: 5622: 100.00		PCGF5_HUMAN (34-334): 1.89e-39: 141: 15.24
+	Mm
		57636 MGAP_MOUSE (1-3065): 0: 5191: 80.91		RING2_MOUSE (1-336): 4.78e-112: 330: 99.70
+	Hs
		1304062 TBX5_HUMAN (9-305): 7.22e-103: 343: 38.93		RING2_HUMAN (1-336): 4.99e-112: 330: 100.00
+	Hs
		171020 TBXT_HUMAN (50-331): 1.62e-103: 342: 35.79		RING1_HUMAN (6-336): 8.6e-69: 222: 51.24
+	Hs
		171072 TBXT_HUMAN (50-331): 1.62e-103: 342: 35.79		PCGF1_HUMAN (28-336): 1.84e-47: 162: 16.88
+	Hs
		1085179 TBR1_HUMAN (39-299): 2.36e-93: 321: 37.18		PCGF1_HUMAN (28-336): 1.84e-47: 162: 16.88