HitPredict

Interactor 1: SFPA2 (Q8IWL1)
Pulmonary surfactant-associated protein A2 (PSP-A) (PSPA) (SP-A) (SP-A2) (35 kDa pulmonary surfactant-associated protein) (Alveolar proteinosis protein) (Collectin-5)
Gene: SFTPA2

Interactor 2: COCA1 (Q99715)
Collagen alpha-1(XII) chain
Gene: COL12A1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	33961781
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	fn3~Lectin_C, Lectin_C~VWA
Common GO terms	GO:0005576 - extracellular region GO:0005615 - extracellular space
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 248 Hs			1 3063
+	Hs
		473765 C1T9A_HUMAN (28-106): 3.69e-12: 67: 46.59		COCA1_HUMAN (1-3015): 0: 1773: 98.55
+	Hs
		70530 C1T9B_HUMAN (28-106): 3.17e-12: 67: 46.59		COCA1_HUMAN (1-3015): 0: 1773: 98.55
+	Hs
		489893 CSPG2_HUMAN (73-247): 2.35e-37: 141: 18.99		PTPRF_HUMAN (1-564): 1.25e-37: 159: 10.71
+	Hs
		490037 CLC4A_HUMAN (112-247): 7.69e-35: 126: 21.68		PTPRF_HUMAN (1-564): 1.25e-37: 159: 10.71
+	Hs
		518018 SFPA2_HUMAN (1-248): 6.11e-54: 175: 100.00		CO6A2_HUMAN (2737-2979): 6.76e-20: 100: 33.70
+	Hs
		518030 COL11_HUMAN (5-248): 4.53e-49: 164: 26.10		CO6A2_HUMAN (2737-2979): 6.76e-20: 100: 33.70
+	Hs
		984715 SFPA2_HUMAN (1-248): 6.11e-54: 175: 100.00		COEA1_HUMAN (2852-3061): 1.05e-11: 73.5: 21.00
+	Hs
		362747 MBL2_HUMAN (35-248): 1.88e-37: 133: 35.81		FINC_HUMAN (9-496): 1.72e-16: 89.3: 9.37
+	Rn
		874725 PGCB_RAT (123-247): 6.3e-38: 142: 25.58		TENR_RAT (10-375): 3.78e-11: 71.6: 12.13
+	Rn
		70327 G3V8R2_RAT (84-247): 4.53e-33: 128: 20.79		B2LYI9_RAT (10-218): 2.01e-10: 69.3: 16.59
+	Hs
		473740 C1T9A_HUMAN (28-106): 3.69e-12: 67: 46.59		CO6A2_HUMAN (2737-2979): 6.76e-20: 100: 33.70
+	Hs
		70502 C1T9B_HUMAN (28-106): 3.17e-12: 67: 46.59		CO6A2_HUMAN (2737-2979): 6.76e-20: 100: 33.70
+	Hs
		517986 CO6A2_HUMAN (34-101): 5.13e-11: 64.3: 46.84		CO9A1_HUMAN (2724-2922): 9.8e-20: 99.4: 27.06
+	Mm
		93247 E9PWQ3_MOUSE (19-152): 1.68e-14: 74.7: 18.49		E9PWQ3_MOUSE (124-399): 1.02e-09: 67: 16.55
+	Hs
		473756 C1T9A_HUMAN (28-106): 3.69e-12: 67: 46.59		COEA1_HUMAN (2852-3061): 1.05e-11: 73.5: 21.00
+	Hs
		70513 C1T9B_HUMAN (28-106): 3.17e-12: 67: 46.59		COEA1_HUMAN (2852-3061): 1.05e-11: 73.5: 21.00
+	Hs
		984701 ADIPO_HUMAN (23-92): 3.96e-11: 63.2: 51.95		COEA1_HUMAN (2852-3061): 1.05e-11: 73.5: 21.00
+	Hs
		358590 C1T9A_HUMAN (28-106): 3.69e-12: 67: 46.59		CO2A1_HUMAN (2782-3053): 1.78e-10: 69.3: 33.14
+	Hs
		70495 C1T9B_HUMAN (28-106): 3.17e-12: 67: 46.59		CO2A1_HUMAN (2782-3053): 1.78e-10: 69.3: 33.14
+	Hs
		473762 C1T9A_HUMAN (28-106): 3.69e-12: 67: 46.59		TITIN_HUMAN (1642-1932): 1.25e-09: 67: 10.51