Interactor 1: HSC20 (Q8IWL3)
Iron-sulfur cluster co-chaperone protein HscB (DnaJ homolog subfamily C member 20) [Cleaved into: Iron-sulfur cluster co-chaperone protein HscB, cytoplasmic (C-HSC20); Iron-sulfur cluster co-chaperone protein HscB, mitochondrial]
Gene: HSCB

Interactor 2: ISCU (Q9H1K1)
Iron-sulfur cluster assembly enzyme ISCU (NifU-like N-terminal domain-containing protein) (NifU-like protein)
Gene: ISCU

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.76 0.60 0.678

The method score is based on:

Property Details
Experiments 24573684, 28380382, 24606901
Identification Methods affinity chromatography technology, pull down, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0005829 - cytosol
GO:0016226 - iron-sulfur cluster assembly
GO:0044571 - [2Fe-2S] cluster assembly
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 235
Hs

1 167
+ At
+ Dm
+ Ec
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024