HitPredict

Interactor 1: BRSK2 (Q8IWQ3)
Serine/threonine-protein kinase BRSK2 (EC 2.7.11.1) (Brain-selective kinase 2) (EC 2.7.11.26) (Brain-specific serine/threonine-protein kinase 2) (BR serine/threonine-protein kinase 2) (Serine/threonine-protein kinase 29) (Serine/threonine-protein kinase SAD-A)
Gene: BRSK2

Interactor 2: BRSK1 (Q8TDC3)
Serine/threonine-protein kinase BRSK1 (EC 2.7.11.1) (Brain-selective kinase 1) (EC 2.7.11.26) (Brain-specific serine/threonine-protein kinase 1) (BR serine/threonine-protein kinase 1) (Serine/threonine-protein kinase SAD-B) (Synapses of Amphids Defective homolog 1) (SAD1 homolog) (hSAD1)
Gene: BRSK1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 32707033
Identification Methods affinity chromatography technology, pull down
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~Pkinase
Common GO terms GO:0000086 - G2/M transition of mitotic cell cycle
GO:0000287 - magnesium ion binding
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
and 14 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 736
Hs

1 778
+ Mm
+ Mm
+ Hs
+ Ce
+ Hs
+ Rn
+ Hs
+ Hs
+ Hs
+ Hs
+ At
+ Hs
+ At
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ At

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024