HitPredict

Interactor 1: TRI59 (Q8IWR1)
Tripartite motif-containing protein 59 (EC 2.3.2.27) (RING finger protein 104) (Tumor suppressor TSBF-1)
Gene: TRIM59

Interactor 2: UBE2W (Q96B02)
Ubiquitin-conjugating enzyme E2 W (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme W) (N-terminal E2 ubiquitin-conjugating enzyme) (EC 2.3.2.25) (N-terminus-conjugating E2) (Ubiquitin carrier protein W) (Ubiquitin-conjugating enzyme 16) (UBC-16) (Ubiquitin-protein ligase W)
Gene: UBE2W

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.555

Property	Details
Experiments	32296183
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	UQ_con~zf-RING_UBOX
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 403 Hs			1 151
+	Hs
		1219286 TRI59_HUMAN (1-403): 1.38e-115: 344: 100.00		Q96FI0_HUMAN (1-148): 1.13e-62: 191: 97.30
+	Hs
		584907 RO52_HUMAN (1-352): 8.74e-78: 249: 16.15		UB2D1_HUMAN (4-150): 2.02e-69: 207: 34.69
+	Hs
		584923 RO52_HUMAN (1-352): 8.74e-78: 249: 16.15		UB2D2_HUMAN (4-150): 1.14e-68: 205: 33.33
+	Hs
		584916 RO52_HUMAN (1-352): 8.74e-78: 249: 16.15		UB2D3_HUMAN (4-150): 3.12e-67: 202: 33.33
+	Hs
		584910 RO52_HUMAN (1-352): 8.74e-78: 249: 16.15		UB2E1_HUMAN (1-150): 3.64e-64: 196: 34.00
+	Hs
		895815 TRI68_HUMAN (1-350): 4.2e-74: 240: 15.24		UB2D3_HUMAN (4-150): 3.12e-67: 202: 33.33
+	Hs
		849366 TRI22_HUMAN (3-337): 9.41e-72: 234: 18.58		UB2D1_HUMAN (4-150): 2.02e-69: 207: 34.69
+	Hs
		849406 TRI11_HUMAN (3-354): 8.45e-72: 234: 19.55		UB2D1_HUMAN (4-150): 2.02e-69: 207: 34.69
+	Hs
		585028 RO52_HUMAN (1-352): 8.74e-78: 249: 16.15		UBE2W_HUMAN (1-151): 1.05e-62: 190: 100.00
+	Hs
		919822 TRI11_HUMAN (3-354): 8.45e-72: 234: 19.55		UB2D2_HUMAN (4-150): 1.14e-68: 205: 33.33
+	Hs
		1336390 TRI39_HUMAN (1-354): 1.52e-69: 229: 16.75		UB2D4_HUMAN (4-150): 7.3e-70: 208: 35.37
+	Hs
		849453 TRI39_HUMAN (1-354): 1.52e-69: 229: 16.75		UB2D1_HUMAN (4-150): 2.02e-69: 207: 34.69
+	Hs
		895876 TRI11_HUMAN (3-354): 8.45e-72: 234: 19.55		UB2D3_HUMAN (4-150): 3.12e-67: 202: 33.33
+	Hs
		919870 TRI39_HUMAN (1-354): 1.52e-69: 229: 16.75		UB2D2_HUMAN (4-150): 1.14e-68: 205: 33.33
+	Hs
		895921 TRI39_HUMAN (1-354): 1.52e-69: 229: 16.75		UB2D3_HUMAN (4-150): 3.12e-67: 202: 33.33
+	Hs
		1297370 TRI39_HUMAN (1-354): 1.52e-69: 229: 16.75		UB2E2_HUMAN (1-150): 3.17e-66: 201: 34.67
+	Hs
		851867 TRI11_HUMAN (3-354): 8.45e-72: 234: 19.55		UB2E1_HUMAN (1-150): 3.64e-64: 196: 34.00
+	Hs
		1282350 TRI39_HUMAN (1-354): 1.52e-69: 229: 16.75		UB2E3_HUMAN (1-150): 1.13e-65: 200: 35.33
+	Hs
		851889 TRI39_HUMAN (1-354): 1.52e-69: 229: 16.75		UB2E1_HUMAN (1-150): 3.64e-64: 196: 34.00
+	Hs
		1284888 TRI39_HUMAN (1-354): 1.52e-69: 229: 16.75		UBE2W_HUMAN (1-151): 1.05e-62: 190: 100.00