Interactor 1: LRC8A (Q8IWT6)
Volume-regulated anion channel subunit LRRC8A (Leucine-rich repeat-containing protein 8A) (HsLRRC8A) (Swelling protein 1)
Gene: LRRC8A

Interactor 2: LRC8C (Q8TDW0)
Volume-regulated anion channel subunit LRRC8C (Factor for adipocyte differentiation 158) (Leucine-rich repeat-containing protein 8C)
Gene: LRRC8C

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 24790029
Identification Methods anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains LRR_8~LRR_8, Pannexin_like~Pannexin_like
Common GO terms GO:0005225 - volume-sensitive anion channel activity
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0015734 - taurine transmembrane transport
GO:0015810 - aspartate transmembrane transport
and 5 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 810
Hs

1 803
+ Mm
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ At
+ Zm
+ At
+ Hs
+ At
+ At

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Last updated: 15 Jul 2024