HitPredict

Interactor 1: LMTK2 (Q8IWU2)
Serine/threonine-protein kinase LMTK2 (EC 2.7.11.1) (Apoptosis-associated tyrosine kinase 2) (Brain-enriched kinase) (hBREK) (CDK5/p35-regulated kinase) (CPRK) (Kinase/phosphatase/inhibitor 2) (Lemur tyrosine kinase 2) (Serine/threonine-protein kinase KPI-2)
Gene: LMTK2

Interactor 2: RFIP5 (Q9BXF6)
Rab11 family-interacting protein 5 (Rab11-FIP5) (Gamma-SNAP-associated factor 1) (Gaf-1) (Phosphoprotein pp75) (Rab11-interacting protein Rip11)
Gene: RAB11FIP5

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005769 - early endosome GO:0005794 - Golgi apparatus GO:0055037 - recycling endosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1503 Hs			1 653
+	Hs
		1168412 LMTK1_HUMAN (14-1500): 0: 702: 29.02		RFIP5_HUMAN (1-653): 4.01e-162: 482: 100.00
+	Hs
		1300022 LMTK3_HUMAN (1-1460): 2.27e-176: 569: 25.82		RFIP5_HUMAN (1-653): 4.01e-162: 482: 100.00
+	Hs
		601582 FGFR2_HUMAN (33-454): 4.84e-123: 406: 20.31		RFIP5_HUMAN (1-653): 4.01e-162: 482: 100.00
+	Hs
		665653 EPHB2_HUMAN (47-544): 2.21e-119: 403: 20.08		RFIP5_HUMAN (1-653): 4.01e-162: 482: 100.00
+	Hs
		508178 FGFR1_HUMAN (36-471): 9.49e-119: 395: 21.20		RFIP5_HUMAN (1-653): 4.01e-162: 482: 100.00
+	Hs
		433981 LYN_HUMAN (86-421): 2.69e-109: 358: 22.19		RFIP5_HUMAN (1-653): 4.01e-162: 482: 100.00
+	Hs
		1167451 LMTK1_HUMAN (14-1500): 0: 702: 29.02		RFIP1_HUMAN (405-650): 1.82e-10: 66.4: 21.14
+	Hs
		1083886 NTRK2_HUMAN (119-410): 3.55e-37: 154: 33.99		RFIP5_HUMAN (1-653): 4.01e-162: 482: 100.00
+	Zm
		38829 A0A1D6MPM7_MAIZE (9-465): 5.71e-137: 443: 19.25		A0A1D6NZ16_MAIZE (144-595): 1.45e-50: 192: 12.53
+	Hs
		385466 NTRK1_HUMAN (131-410): 1.29e-36: 152: 33.33		RFIP5_HUMAN (1-653): 4.01e-162: 482: 100.00
+	Ce
		136783 O17566_CAEEL (133-988): 5.92e-144: 475: 17.45		UNC89_CAEEL (164-653): 4.53e-35: 145: 9.40
+	Hs
		1088139 DDR2_HUMAN (107-407): 8.37e-32: 137: 30.49		RFIP5_HUMAN (1-653): 4.01e-162: 482: 100.00
+	Hs
		1081594 NTRK3_HUMAN (131-410): 1.24e-31: 136: 28.25		RFIP5_HUMAN (1-653): 4.01e-162: 482: 100.00
+	Hs
		297808 LYN_HUMAN (86-421): 2.69e-109: 358: 22.19		K0754_HUMAN (146-604): 1.96e-33: 140: 9.61
+	Hs
		508071 FGFR1_HUMAN (36-471): 9.49e-119: 395: 21.20		RFIP1_HUMAN (405-650): 1.82e-10: 66.4: 21.14
+	Hs
		433842 LYN_HUMAN (86-421): 2.69e-109: 358: 22.19		RFIP1_HUMAN (405-650): 1.82e-10: 66.4: 21.14
+	Hs
		384297 NTRK1_HUMAN (131-410): 1.29e-36: 152: 33.33		DNMT1_HUMAN (300-605): 6.36e-41: 162: 15.02
+	Hs
		385038 NTRK1_HUMAN (131-410): 1.29e-36: 152: 33.33		RFIP1_HUMAN (405-650): 1.82e-10: 66.4: 21.14
+	Hs
		385252 NTRK1_HUMAN (131-410): 1.29e-36: 152: 33.33		TITIN_HUMAN (213-603): 8.37e-10: 64.5: 8.70
+	Hs
		1081515 NTRK3_HUMAN (131-410): 1.24e-31: 136: 28.25		RFIP1_HUMAN (405-650): 1.82e-10: 66.4: 21.14