HitPredict

Interactor 1: SULF2 (Q8IWU5)
Extracellular sulfatase Sulf-2 (hSulf-2) (Arylsulfatase) (EC 3.1.6.1) (N-acetylglucosamine-6-sulfatase) (EC 3.1.6.14) [Cleaved into: Extracellular sulfatase Sulf-2 secreted form]
Gene: SULF2

Interactor 2: SULF1 (Q8IWU6)
Extracellular sulfatase Sulf-1 (hSulf-1) (Arylsulfatase) (EC 3.1.6.1) (N-acetylglucosamine-6-sulfatase) (EC 3.1.6.14) [Cleaved into: Extracellular sulfatase Sulf-2 secreted form]
Gene: SULF1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Sulfatase~Sulfatase
Common GO terms GO:0001822 - kidney development
GO:0002063 - chondrocyte development
GO:0003094 - glomerular filtration
GO:0004065 - arylsulfatase activity
GO:0005509 - calcium ion binding
and 18 others

more...
Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 870
Hs

1 871
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024