HitPredict

Interactor 1: RHG12 (Q8IWW6)
Rho GTPase-activating protein 12 (Rho-type GTPase-activating protein 12)
Gene: ARHGAP12

Interactor 2: RHOV (Q96L33)
Rho-related GTP-binding protein RhoV (CDC42-like GTPase 2) (GTP-binding protein-like 2) (Rho GTPase-like protein ARHV) (Wnt-1 responsive Cdc42 homolog 2) (WRCH-2)
Gene: RHOV

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~Ras, Ras~RhoGAP
Common GO terms	GO:0007015 - actin filament organization
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 846 Hs			1 236
+	Hs
		925420 RHG12_HUMAN (1-846): 0: 802: 100.00		RAC1_HUMAN (32-217): 3.34e-76: 230: 53.23
+	Hs
		925378 RHG27_HUMAN (11-845): 3.56e-169: 514: 32.45		RAC1_HUMAN (32-217): 3.34e-76: 230: 53.23
+	Hs
		894152 RHG27_HUMAN (11-845): 3.56e-169: 514: 32.45		CDC42_HUMAN (32-207): 2.12e-66: 205: 57.39
+	Hs
		70701 MYO9A_HUMAN (69-840): 2.1e-102: 351: 15.83		RHOV_HUMAN (1-236): 3.37e-76: 231: 100.00
+	Hs
		70663 MYO9A_HUMAN (69-840): 2.1e-102: 351: 15.83		RHOA_HUMAN (33-215): 9.31e-73: 221: 42.62
+	Hs
		951062 RHG21_HUMAN (78-846): 3.01e-97: 336: 21.24		RHOG_HUMAN (31-210): 1.12e-78: 236: 49.44
+	Hs
		925343 RHG21_HUMAN (78-846): 3.01e-97: 336: 21.24		RAC1_HUMAN (32-217): 3.34e-76: 230: 53.23
+	Sp
		251348 RGA4_SCHPO (63-844): 2.95e-88: 301: 16.40		CDC42_SCHPO (32-217): 1.58e-88: 261: 52.15
+	Hs
		925329 RHG15_HUMAN (431-845): 4.37e-104: 331: 46.80		RAC1_HUMAN (32-217): 3.34e-76: 230: 53.23
+	Hs
		892420 RHG21_HUMAN (78-846): 3.01e-97: 336: 21.24		RAC3_HUMAN (32-206): 6.17e-74: 224: 56.00
+	Hs
		564562 RHG21_HUMAN (78-846): 3.01e-97: 336: 21.24		RHOQ_HUMAN (23-236): 1.99e-73: 223: 50.00
+	Hs
		545426 RHG21_HUMAN (78-846): 3.01e-97: 336: 21.24		RAC2_HUMAN (32-216): 6.11e-73: 222: 52.43
+	Hs
		900564 RHG21_HUMAN (78-846): 3.01e-97: 336: 21.24		RHOA_HUMAN (33-215): 9.31e-73: 221: 42.62
+	Hs
		70662 MYO9A_HUMAN (69-840): 2.1e-102: 351: 15.83		CDC42_HUMAN (32-207): 2.12e-66: 205: 57.39
+	Hs
		900443 MYO9B_HUMAN (52-840): 3.46e-94: 327: 17.69		RHOA_HUMAN (33-215): 9.31e-73: 221: 42.62
+	Hs
		925690 RHG23_HUMAN (132-844): 2.77e-90: 314: 17.31		RAC1_HUMAN (32-217): 3.34e-76: 230: 53.23
+	Hs
		894109 RHG21_HUMAN (78-846): 3.01e-97: 336: 21.24		CDC42_HUMAN (32-207): 2.12e-66: 205: 57.39
+	Hs
		901000 RHG23_HUMAN (132-844): 2.77e-90: 314: 17.31		RHOA_HUMAN (33-215): 9.31e-73: 221: 42.62
+	Hs
		893974 MYO9B_HUMAN (52-840): 3.46e-94: 327: 17.69		CDC42_HUMAN (32-207): 2.12e-66: 205: 57.39
+	Hs
		1133703 RHG21_HUMAN (78-846): 3.01e-97: 336: 21.24		RHOJ_HUMAN (32-214): 8.3e-59: 186: 50.27