HitPredict

Interactor 1: RHG12 (Q8IWW6)
Rho GTPase-activating protein 12 (Rho-type GTPase-activating protein 12)
Gene: ARHGAP12

Interactor 2: ZO2 (Q9UDY2)
Tight junction protein ZO-2 (Tight junction protein 2) (Zona occludens protein 2) (Zonula occludens protein 2)
Gene: TJP2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.77	0.80	0.788

Property	Details
Experiments	34079125, 32203420, 33961781, unassigned2213
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Guanylate_kin~SH3_1, SH3_1~SH3_2
Common GO terms	-
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 846 Hs			1 1190
+	Hs
		1133715 RHG21_HUMAN (78-846): 3.01e-97: 336: 21.24		ZO2_HUMAN (1-1190): 0: 838: 100.00
+	Hs
		1345231 RHG35_HUMAN (392-844): 4.72e-71: 258: 19.72		ZO2_HUMAN (1-1190): 0: 838: 100.00
+	Hs
		506670 BCR_HUMAN (632-819): 7.58e-25: 113: 39.27		ZO2_HUMAN (1-1190): 0: 838: 100.00
+	Mm
		886881 RHG39_MOUSE (92-844): 1.19e-75: 269: 14.07		DLG4_MOUSE (3-423): 3.16e-52: 198: 18.89
+	Mm
		1143388 RHG32_MOUSE (603-844): 1.13e-72: 263: 30.00		DLG4_MOUSE (3-423): 3.16e-52: 198: 18.89
+	Mm
		1131438 ABR_MOUSE (301-846): 3.63e-70: 250: 20.39		DLG4_MOUSE (3-423): 3.16e-52: 198: 18.89
+	Hs
		1271026 RGAP1_HUMAN (359-837): 1.26e-72: 252: 18.56		DLG3_HUMAN (2-318): 5.99e-23: 107: 16.61