HitPredict

Interactor 1: UN45B (Q8IWX7)
Protein unc-45 homolog B (Unc-45B) (SMUNC45)
Gene: UNC45B

Interactor 2: CHIP (Q9UNE7)
E3 ubiquitin-protein ligase CHIP (EC 2.3.2.27) (Antigen NY-CO-7) (CLL-associated antigen KW-8) (Carboxy terminus of Hsp70-interacting protein) (RING-type E3 ubiquitin transferase CHIP) (STIP1 homology and U box-containing protein 1)
Gene: STUB1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	34057440
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0030018 - Z disc GO:0051879 - Hsp90 protein binding
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 931 Hs			1 303
+	Hs
		1234379 UN45A_HUMAN (6-929): 0: 924: 56.65		WDTC1_HUMAN (21-272): 3.45e-30: 122: 18.82
+	Hs
		1078491 UN45A_HUMAN (6-929): 0: 924: 56.65		TOM34_HUMAN (26-117): 9.37e-11: 63.5: 35.87
+	Ce
		105585 G5EG62_CAEEL (4-928): 0: 800: 30.62		G5ECY6_CAEEL (26-301): 5.16e-47: 160: 38.77
+	Hs
		1357469 CHIP_HUMAN (6-146): 9.82e-37: 142: 27.66		CHIP_HUMAN (1-303): 3.8e-69: 218: 100.00
+	Mm
		1376714 CHIP_MOUSE (6-146): 9.32e-37: 142: 27.66		CHIP_MOUSE (1-303): 1.23e-67: 214: 97.37
+	Mm
		1141207 PPP5_MOUSE (4-155): 1e-36: 147: 27.45		PPP5_MOUSE (1-259): 7.23e-36: 136: 20.91
+	Hs
		858598 PPP5_HUMAN (2-155): 1.26e-36: 147: 28.39		PPP5_HUMAN (1-259): 1.3e-35: 135: 20.91
+	Ps
		1341481 TOC64_PEA (3-125): 2.03e-37: 151: 34.15		TOC64_PEA (4-137): 3.99e-33: 129: 28.36
+	Hs
		174501 OGT1_HUMAN (6-407): 2.59e-28: 124: 12.90		TOM70_HUMAN (4-212): 8.69e-40: 148: 22.47
+	Rn
		251112 SGTA_RAT (4-126): 1.41e-37: 145: 32.52		SGTA_RAT (3-140): 5.31e-33: 125: 28.99
+	Hs
		213414 SGTA_HUMAN (4-126): 6.85e-37: 143: 30.89		SGTA_HUMAN (3-140): 2.4e-33: 126: 29.71
+	Hs
		858652 PPP5_HUMAN (2-155): 1.26e-36: 147: 28.39		WDTC1_HUMAN (21-272): 3.45e-30: 122: 18.82
+	Mm
		1206764 SGTA_MOUSE (4-126): 2.74e-37: 144: 32.52		SGTA_MOUSE (4-140): 2.54e-32: 123: 28.47
+	Mm
		1194963 CHIP_MOUSE (6-146): 9.32e-37: 142: 27.66		WDTC1_MOUSE (21-272): 7.36e-30: 120: 19.22
+	Hs
		174743 OGT1_HUMAN (6-407): 2.59e-28: 124: 12.90		PPP5_HUMAN (1-259): 1.3e-35: 135: 20.91
+	Hs
		213490 STIP1_HUMAN (4-427): 5.12e-27: 118: 12.82		SGTA_HUMAN (3-140): 2.4e-33: 126: 29.71
+	Dm
		1366835 Q9VH81_DROME (4-222): 5.22e-36: 145: 18.75		Q9VPN5_DROME (26-202): 1.32e-15: 78.6: 17.30
+	Hs
		213621 SGTA_HUMAN (4-126): 6.85e-37: 143: 30.89		SGTB_HUMAN (70-177): 7.78e-10: 60.8: 18.52
+	Hs
		174456 OGT1_HUMAN (6-407): 2.59e-28: 124: 12.90		KDM6A_HUMAN (25-206): 2.59e-10: 63.1: 13.02