HitPredict

Interactor 1: PSD12 (O00232)
26S proteasome non-ATPase regulatory subunit 12 (26S proteasome regulatory subunit RPN5) (26S proteasome regulatory subunit p55)
Gene: PSMD12

Interactor 2: EIF3M (Q7L2H7)
Eukaryotic translation initiation factor 3 subunit M (eIF3m) (Fetal lung protein B5) (hFL-B5) (PCI domain-containing protein 1)
Gene: EIF3M

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.75	1.00	0.871

Property	Details
Experiments	28514442, 33961781, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	PCI~PCI
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 456 Hs			1 374
+	Hs
		122105 PSD12_HUMAN (1-456): 2.11e-155: 449: 100.00		PSD13_HUMAN (71-369): 5.95e-102: 307: 15.64
+	Dm
		1180999 Q9V3Z4_DROME (11-455): 4.84e-121: 364: 46.67		Q7KMP8_DROME (71-369): 8.26e-82: 256: 15.58
+	Hs
		121872 PSD11_HUMAN (27-443): 9.3e-90: 281: 15.44		PSD13_HUMAN (71-369): 5.95e-102: 307: 15.64
+	Sc
		978511 RPN5_YEAST (14-456): 3.37e-106: 324: 40.67		RPN9_YEAST (71-370): 3.78e-59: 198: 12.69
+	Mm
		291856 CSN4_MOUSE (45-448): 1.94e-100: 307: 19.37		CSN2_MOUSE (83-370): 8.93e-51: 177: 13.27
+	Hs
		897302 CSN4_HUMAN (45-448): 2.23e-100: 307: 19.37		CSN2_HUMAN (83-370): 8.93e-51: 177: 13.27
+	Hs
		1311900 CSN4_HUMAN (45-448): 2.23e-100: 307: 19.37		CSN7B_HUMAN (178-370): 7.88e-49: 167: 20.81
+	Hs
		1311913 CSN4_HUMAN (45-448): 2.23e-100: 307: 19.37		CSN7A_HUMAN (190-370): 4.22e-48: 166: 22.16
+	Hs
		897224 CSN2_HUMAN (24-439): 1.11e-94: 294: 12.59		CSN2_HUMAN (83-370): 8.93e-51: 177: 13.27
+	Hs
		897312 CSN2_HUMAN (24-439): 1.11e-94: 294: 12.59		CSN7B_HUMAN (178-370): 7.88e-49: 167: 20.81
+	Hs
		897324 CSN2_HUMAN (24-439): 1.11e-94: 294: 12.59		CSN7A_HUMAN (190-370): 4.22e-48: 166: 22.16
+	Hs
		121722 PSD11_HUMAN (27-443): 9.3e-90: 281: 15.44		CSN2_HUMAN (83-370): 8.93e-51: 177: 13.27
+	Mm
		897342 CSN2_MOUSE (24-439): 1.11e-94: 294: 12.59		CSN7A_MOUSE (190-370): 9.16e-48: 164: 21.62
+	Dm
		1358197 CSN4_DROME (45-450): 1.98e-91: 284: 20.00		CSN7_DROME (177-369): 2.08e-48: 166: 22.84
+	At
		1278364 PSD11_ARATH (27-442): 4.61e-90: 281: 16.40		CSN7_ARATH (180-373): 2.04e-48: 166: 24.62
+	Dm
		1277031 CSN2_DROME (24-439): 2.23e-88: 278: 12.09		CSN7_DROME (177-369): 2.08e-48: 166: 22.84
+	Dm
		1277030 CSN4_DROME (45-450): 1.98e-91: 284: 20.00		CSN2_DROME (83-370): 9.19e-42: 153: 10.88
+	Dm
		1277029 CSN2_DROME (24-439): 2.23e-88: 278: 12.09		CSN2_DROME (83-370): 9.19e-42: 153: 10.88
+	An
		961357 CSN2_EMENI (24-437): 1.27e-90: 285: 14.25		CSN7_EMENI (178-370): 4.29e-32: 124: 19.32
+	An
		1124313 CSN2_EMENI (24-437): 1.27e-90: 285: 14.25		CSN2_EMENI (123-362): 1.48e-25: 109: 14.98