HitPredict

Interactor 1: MIRO2 (Q8IXI1)
Mitochondrial Rho GTPase 2 (MIRO-2) (hMiro-2) (EC 3.6.5.-) (Ras homolog gene family member T2)
Gene: RHOT2

Interactor 2: MIRO1 (Q8IXI2)
Mitochondrial Rho GTPase 1 (MIRO-1) (hMiro-1) (EC 3.6.5.-) (Rac-GTP-binding protein-like protein) (Ras homolog gene family member T1)
Gene: RHOT1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.74 1.00 0.861

The method score is based on:

Property Details
Experiments 28514442, 32877691, 33961781
Identification Methods affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains EF_assoc_1~EF_assoc_2, EF_assoc_1~Ras, Ras~Ras
Common GO terms GO:0003924 - GTPase activity
GO:0005509 - calcium ion binding
GO:0005525 - GTP binding
GO:0005739 - mitochondrion
GO:0005741 - mitochondrial outer membrane
and 8 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 618
Hs

1 618
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024