HitPredict

Interactor 1: MIRO1 (Q8IXI2)
Mitochondrial Rho GTPase 1 (MIRO-1) (hMiro-1) (EC 3.6.5.-) (Rac-GTP-binding protein-like protein) (Ras homolog gene family member T1)
Gene: RHOT1

Interactor 2: PKHA4 (Q9H4M7)
Pleckstrin homology domain-containing family A member 4 (PH domain-containing family A member 4) (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1)
Gene: PLEKHA4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	31091453
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~Ras
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 618 Hs			1 779
+	Hs
		1220660 MIRO2_HUMAN (1-618): 0: 764: 59.81		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		918949 RAB1A_HUMAN (5-190): 5.36e-74: 237: 20.21		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		925616 RAC1_HUMAN (3-181): 7.62e-73: 234: 23.83		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		925254 RAC1_HUMAN (3-181): 7.62e-73: 234: 23.83		GAB1_HUMAN (52-611): 6.48e-53: 197: 13.92
+	Hs
		1035374 RAB35_HUMAN (5-168): 1.96e-72: 233: 25.90		GAB1_HUMAN (52-611): 6.48e-53: 197: 13.92
+	Hs
		925738 RAC1_HUMAN (3-181): 7.62e-73: 234: 23.83		TBD2B_HUMAN (53-512): 3.31e-51: 195: 17.57
+	Hs
		925241 RAC1_HUMAN (3-181): 7.62e-73: 234: 23.83		TIAM1_HUMAN (2-634): 3.43e-44: 174: 12.28
+	Hs
		1022394 RAB35_HUMAN (5-168): 1.96e-72: 233: 25.90		TIAM1_HUMAN (2-634): 3.43e-44: 174: 12.28
+	Hs
		925615 RAC1_HUMAN (3-181): 7.62e-73: 234: 23.83		OSBL3_HUMAN (52-563): 4.71e-44: 173: 11.36
+	Hs
		925343 RAC1_HUMAN (3-181): 7.62e-73: 234: 23.83		RHG21_HUMAN (22-662): 1.96e-43: 172: 13.18
+	Hs
		925705 RAC1_HUMAN (3-181): 7.62e-73: 234: 23.83		SWP70_HUMAN (55-446): 3.06e-44: 170: 11.36
+	Mm
		925795 RAC1_MOUSE (3-181): 7.62e-73: 234: 23.83		TIAM1_MOUSE (2-634): 2.04e-40: 163: 12.13
+	Rn
		88818 RAC1_RAT (3-181): 7.62e-73: 234: 23.83		D3ZWV8_RAT (2-634): 1.21e-39: 160: 11.65
+	Hs
		1066121 RAB35_HUMAN (5-168): 1.96e-72: 233: 25.90		ACAP2_HUMAN (28-517): 6.24e-39: 156: 13.10
+	Hs
		925632 RAC1_HUMAN (3-181): 7.62e-73: 234: 23.83		PKHA1_HUMAN (16-261): 3.76e-39: 151: 16.92
+	Hs
		925629 RAC1_HUMAN (3-181): 7.62e-73: 234: 23.83		PKHA5_HUMAN (2-653): 1.62e-36: 150: 17.61
+	Hs
		925394 RAC1_HUMAN (3-181): 7.62e-73: 234: 23.83		RHG22_HUMAN (29-181): 1.62e-33: 139: 26.95
+	Mm
		925805 RAC1_MOUSE (3-181): 7.62e-73: 234: 23.83		RHG22_MOUSE (33-181): 1.33e-31: 133: 25.77
+	Hs
		925760 RAC1_HUMAN (3-181): 7.62e-73: 234: 23.83		FARP1_HUMAN (6-167): 1.07e-24: 112: 17.96
+	Hs
		925603 RAC1_HUMAN (3-181): 7.62e-73: 234: 23.83		TARA_HUMAN (49-471): 7.83e-20: 97.3: 15.21