Interactor 1: SIR2 (Q8IXJ6)
NAD-dependent protein deacetylase sirtuin-2 (EC 2.3.1.286) (NAD-dependent protein defatty-acylase sirtuin-2) (EC 2.3.1.-) (Regulatory protein SIR2 homolog 2) (SIR2-like protein 2)
Gene: SIRT2
Interactor 2: SIR2 (Q8IXJ6)
NAD-dependent protein deacetylase sirtuin-2 (EC 2.3.1.286) (NAD-dependent protein defatty-acylase sirtuin-2) (EC 2.3.1.-) (Regulatory protein SIR2 homolog 2) (SIR2-like protein 2)
Gene: SIRT2
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.38 | 1.00 | 0.618 |
The method score is based on:
Property | Details |
---|---|
Experiments | 35066290 |
Identification Methods | affinity chromatography technology |
Interaction Type | physical association |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | SIR2~SIR2 |
Common GO terms | GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000183 - rDNA heterochromatin formation GO:0000781 - chromosome, telomeric region GO:0000792 - heterochromatin GO:0003682 - chromatin binding and 83 others more... |
Homologous interactions | 11 |
Homologous interactions
Color coding for hit scores
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024