Interactor 1: ASXL1 (Q8IXJ9)
Polycomb group protein ASXL1 (Additional sex combs-like protein 1)
Gene: ASXL1

Interactor 2: BAP1 (Q92560)
Ubiquitin carboxyl-terminal hydrolase BAP1 (EC 3.4.19.12) (BRCA1-associated protein 1) (Cerebral protein 6)
Gene: BAP1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.989

The method score is based on:

Property Details
Experiments 27705803, 32683582, 33758188, 32669118, 34170818, 34186160, 21642991, 26416890, 26739236, 26437366, 33961781, 34591877, 36865140, 36991118, 19615732, 19815555, 20436459, 20805357, 22897849
Identification Methods affinity chromatography technology, pull down, biochemical, x-ray crystallography, anti tag coimmunoprecipitation, tandem affinity purification, anti bait coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains ASXH~Peptidase_C12, ASXH~UCH_C
Common GO terms GO:0003682 - chromatin binding
GO:0005654 - nucleoplasm
GO:0035517 - PR-DUB complex
Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 1541
Hs

1 729
+ Mm
+ Hs
+ Hs
+ Mm
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024